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GlossaryLIM Homeobox 2

gene encoding a protein crucial for hair follicle development

LIM Homeobox 2 (Lhx2) is a gene that encodes a transcription factor, which is a type of protein that helps control the activity of other genes. It plays a crucial role in the development of various tissues, including the brain and hair follicles. In the context of hair, Lhx2 is essential for the proper formation and cycling of hair follicles, making it significant in studies related to hair growth and conditions like alopecia.

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Whole-Genome Sequencing of Eight Goat Populations for the Detection of Selection Signatures Underlying Production and Adaptive Traits

research Whole-Genome Sequencing of Eight Goat Populations for the Detection of Selection Signatures Underlying Production and Adaptive Traits

92 citations, December 2016 in “Scientific Reports”

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

research Hair in Health and Disease: An Introduction

3 citations, January 2012 in “Wageningen Academic Publishers eBooks”

Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.

research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche

133 citations, September 2013 in “Nature Reviews Molecular Cell Biology”

Different types of stem cells and their environments are key to skin repair and maintenance.

research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

96 citations, July 2014 in “Cold Spring Harbor Perspectives in Medicine”

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle

44 citations, June 2018 in “Journal of Cellular Physiology”

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

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community Started oral minoxidil today

in Minoxidil 7 upvotes 6 years ago

A user started taking oral minoxidil using Rogaine, despite concerns from others about its safety and proper use. They plan to update on their progress.

community Kintor stealing pictures from a hair transplant clinic to promote their failed product (KX826, Pyrilutamide)

in Product 315 upvotes 3 months ago

Kintor is accused of using fake pictures to promote their product, Pyrilutamide (KX826), which failed Phase 3 trials. Users express disappointment and note similar false advertising has occurred with finasteride and minoxidil.

community KX-826 Phase 3 Failed. Sorry guys...

in Research/Science 52 upvotes 11 months ago

The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.