Expression and Distribution Patterns of Spermine, Spermidine, and Putrescine in Rat Hair Follicle
November 2017
in “
Histochemistry and Cell Biology
”
TLDR Polyamines are abundant in certain parts of rat hair follicles and may play a key role in hair growth.
The study examined the expression and distribution of polyamines—spermine, spermidine, and putrescine—in rat hair follicles, revealing that these compounds were most abundant in the matrix, Huxley’s layer, deeper Henle’s layer, and the cuticle of the inner root sheath/hair cuticle. This suggested that these areas had a higher biological potential in anagen hair follicles, potentially playing a critical role in hair growth. Additionally, differences in staining patterns between spermine/spermidine and putrescine in epidermal cells and fibroblasts were observed, indicating possible applications for these findings in researching hair cycles and epidermal tumor genesis.