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GlossarySpermine

naturally occurring compound involved in cellular metabolism and DNA stabilization

Spermine is a naturally occurring polyamine compound found in all eukaryotic cells. It plays a crucial role in cellular metabolism and is involved in stabilizing the structure of DNA, RNA, and various proteins. In the context of hair and alopecia, spermine has been studied for its potential effects on hair growth and follicle health.

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research Topical Spermine And Putrescine Stimulated DNA Synthesis In The Hairless Mouse Epidermis

10 citations, July 1980 in “British Journal of Dermatology”

Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.

research Spermidine/spermine-N¹-acetyltransferase: a key metabolic regulator

305 citations, March 2008 in “AJP Endocrinology and Metabolism”

research Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

54 citations, February 2002 in “Carcinogenesis”

research Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

43 citations, February 1999 in “Biochemical Journal”

research Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

13 citations, March 1999 in “Biochemical Journal”

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