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    Glossary Spermine

    naturally occurring compound involved in cellular metabolism and DNA stabilization

    Spermine is a naturally occurring polyamine compound found in all eukaryotic cells. It plays a crucial role in cellular metabolism and is involved in stabilizing the structure of DNA, RNA, and various proteins. In the context of hair and alopecia, spermine has been studied for its potential effects on hair growth and follicle health.

    Research 10 of 87

    1. Spermidine/spermine-<i>N</i><sup>1</sup>-acetyltransferase: a key metabolic regulator AJP Endocrinology and Metabolism · 2008 · 305 citations
    2. Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA Journal of Biological Chemistry · 2006 · 128 citations
    3. Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase Journal of Biological Chemistry · 1997 · 124 citations
    4. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 43 citations
    5. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue Biochemical Journal · 1999 · 13 citations
    6. Topical spermine and putrescine stimulated DNA synthesis in the hairless mouse epidermis British Journal of Dermatology · 1980 · 10 citations
    7. Expression and distribution patterns of spermine, spermidine, and putrescine in rat hair follicle Histochemistry and Cell Biology · 2017 · 2 citations
    8. Spermine Lipid Assembled Nanoparticles for siRNA Delivery and Androgenetic Alopecia Therapy ACS Applied Materials & Interfaces · 2026
    9. Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis Carcinogenesis · 2002 · 54 citations
    10. Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase Journal of Investigative Dermatology · 2001 · 54 citations
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