The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle

    July 2009 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Lutz Langbein, Hiroshi Yoshida, Silke Praetzel-Wunder … Jürgen Schweizer
    Studysummary This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.
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    Research cited in this study 22

    1. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    2. Three-Dimensional Modelling of Interchain Sequence Similarities and Differences in the Coiled-Coil Segments of Keratin Intermediate Filament Heterodimers Highlight Features Important in Assembly Journal of Structural Biology · 2007
    3. Novel Type I Hair Keratins K39 And K40 Are The Last To Be Expressed In Differentiation Of The Hair: Completion Of The Human Hair Keratin Catalog Journal of Investigative Dermatology · 2007
    4. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), And K28 (K25irs4) Represent The Type I Inner Root Sheath Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2006
    5. Characterization of New Members of the Human Type II Keratin Gene Family and a General Evaluation of the Keratin Gene Domain on Chromosome 12q13.13 Journal of Investigative Dermatology · 2005
    6. Keratins of the Human Hair Follicle International review of cytology · 2005
    7. The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain Differentiation · 2004
    8. Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes Journal of Investigative Dermatology · 2004
    9. Hair Keratins And Hair Follicle-Specific Epithelial Keratins Methods in cell biology · 2004
    10. Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles Journal of Investigative Dermatology · 2003
    11. K6irs1, K6irs2, K6irs3, And K6irs4 Represent The Inner-Root-Sheath-Specific Type II Epithelial Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2003
    12. A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2002
    13. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    14. In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments ˜The œjournal of cell biology/˜The œJournal of cell biology · 2000
    15. Keratin 17 Expression in the Hard Epithelial Context of the Hair and Nail, and Its Relevance for the Pachyonychia Congenita Phenotype Journal of Investigative Dermatology · 2000
    16. The Catalog of Human Hair Keratins Journal of biological chemistry/˜The œJournal of biological chemistry · 1999
    17. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    18. Androgens and Human Hair Growth Clinical endocrinology · 1994
    19. Structural Features and Sites of Expression of a New Murine 65 kD and 48 kD Hair-Related Keratin Pair, Associated with a Special Type of Parakeratotic Epithelial Differentiation Differentiation · 1992
    20. Expression of Hair-Related Keratins in a Soft Epithelium: Subpopulations of Human and Mouse Dorsal Tongue Keratinocytes Express Keratin Markers for Hair, Skin, and Esophageal Types of Differentiation Experimental Cell Research · 1989
    21. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    22. Characterization of the Proteins of Guinea-Pig Hair and Hair-Follicle Tissue Biochemical Journal · 1973

    Related research 5

    1. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    2. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    3. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003
    4. Structure and Site of Expression of a Murine Type II Hair Keratin Molecular Biology Reports · 1992
    5. Keratin 19: Predicted Amino Acid Sequence and Broad Tissue Distribution Suggest It Evolved from Keratinocyte Keratins Journal of Investigative Dermatology · 1989