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    Glossary Epithelial Keratins

    Epithelial keratins are a group of fibrous proteins that form a key component of the cytoskeleton in epithelial cells, including those in the hair follicle. They play a crucial role in maintaining the structural integrity and resilience of hair and skin. In the context of hair loss, abnormalities or mutations in keratin genes can lead to conditions such as alopecia or other hair disorders, highlighting their importance in hair biology and health. Key distinguishing characteristics include their ability to form intermediate filaments, which provide mechanical support and protection to cells.

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    1. Hair Keratins and Hair Follicle–Specific Epithelial Keratins Methods in cell biology · 2004 · 31 citations
    2. Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study Journal of Cutaneous Pathology · 2005 · 27 citations
    3. Expression patterns of hair-related keratins and epithelial keratins in onychopapilloma: The significance of clarifying the origin of onychopapilloma Frontiers in Medicine · 2022 · 3 citations
    4. Immunhistochemische und biochemische Untersuchungen zur Expression von epithelialen Keratinen in klinisch unveränderter Pferdehaut und Fußhaut von Kaltblutpferden mit Warzenmauke-Syndrom 2007
    5. Induction of Hard Keratin Expression in Non-Nail-Matrical Keratinocytes by Nail-Matrical Fibroblasts through Epithelial-Mesenchymal Interactions Plastic & Reconstructive Surgery · 2003 · 25 citations
    6. Assembly of Hair Keratins in Transfected Epithelial Cells Biochemical and Biophysical Research Communications · 1996 · 5 citations
    7. Epithelial keratin and filaggrin expression in seborrheic keratosis: evaluation based on histopathological classification International Journal of Dermatology · 2013 · 12 citations
    8. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    9. Structural features and sites of expression of a new murine 65 kD and 48 kD hair-related keratin pair, associated with a special type of parakeratotic epithelial differentiation Differentiation · 1992 · 28 citations
    10. Keratin cytoskeletons in epithelial cells of internal organs Proceedings of the National Academy of Sciences · 1979 · 482 citations
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    1. Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling Reddit · 26 Oct 2025

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