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    Glossary Cytokeratins

    fibrous proteins providing structural support in epithelial cells

    Cytokeratins, also known as keratin proteins or CKs, are a group of fibrous structural proteins that form the intermediate filaments in epithelial cells. They provide mechanical support and help maintain the integrity of cells and tissues. In a clinical context, cytokeratins are often used as biomarkers in the diagnosis and study of various cancers, as their expression patterns can indicate the type and origin of a tumor.

    Research 10 of 1000+

    1. Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. The Journal of Cell Biology · 1982 · 277 citations
    2. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles Differentiation · 1988 · 248 citations
    3. Cytokeratins as Markers of Follicular Differentiation American Journal of Dermatopathology · 2001 · 121 citations
    4. Immunohistochemical localization of cytokeratins and involucrin in calcifying epithelioma: comparative studies with normal skin British Journal of Dermatology · 2006 · 49 citations
    5. A Novel Type II Cytokeratin, mK6irs, is Expressed in the Huxley and Henle Layers of the Mouse Inner Root Sheath Journal of Investigative Dermatology · 2001 · 45 citations
    6. Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2. PubMed · 1992 · 31 citations
    7. Trichofolliculoma: case report with immunohistochemical study of cytokeratins 2003 · 18 citations
    8. Keratinisation status and cytokeratins of the human Meibomian gland epithelium Acta Ophthalmologica · 2009 · 5 citations
    9. Immunolocalization of cytokeratins in some freshly fixed bovine epithelia. PubMed · 1991 · 4 citations
    10. Immunostaining study of cytokeratins in human hair follicle development 2020 · 2 citations
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