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    Cellular Retinol-Binding Protein-1 Expression Increases with Clinical Severity of Alopecia Areata

    December 2018 in “ Journal of cosmetic dermatology ”
    Eman Hamed Elmaadawy, Lamia Hamouda Elgarhy, Mohammad Shareef
    Studysummary This study observed a significant increase in cellular retinol-binding protein-1 expression in lesional skin of patients with alopecia areata compared to healthy controls, suggesting its potential role in the disease's pathogenesis.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 8

    1. Endogenous Retinoids in the Pathogenesis of Alopecia Areata ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    2. Endogenous Retinoids in the Hair Follicle and Sebaceous Gland Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2011
    3. Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata British Journal of Dermatology · 2011
    4. Phase I/II Randomized Bilateral Half-Head Comparison of Topical Bexarotene 1% Gel for Alopecia Areata Journal of the American Academy of Dermatology · 2009
    5. Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin Journal of biological chemistry/˜The œJournal of biological chemistry · 2008
    6. Immunolocalization of Enzymes, Binding Proteins, and Receptors Sufficient for Retinoic Acid Synthesis and Signaling During the Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    7. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005
    8. Topical Tretinoin as an Adjunctive Therapy with Intralesional Triamcinolone Acetonide for Alopecia Areata: Clinical Experience in Northern Saudi Arabia International Journal of Dermatology · 1997

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019