Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata

    Keun Jae Ahn, Eunhee Choi, J. Kim … S.B. Cho
    Studysummary This study found that individuals with alopecia areata had significantly higher serum levels of retinol-binding protein 4 and increased IgG immunoreactivity against it, suggesting a role in the disease's pathogenesis.
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    Research cited in this study 7

    1. Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes Histochemistry and cell biology · 2010
    2. Trichohyalin Is a Potential Major Autoantigen in Human Alopecia Areata Journal of Proteome Research · 2010
    3. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    4. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    5. Phase I/II Randomized Bilateral Half-Head Comparison of Topical Bexarotene 1% Gel for Alopecia Areata Journal of the American Academy of Dermatology · 2009
    6. Immunolocalization of Enzymes, Binding Proteins, and Receptors Sufficient for Retinoic Acid Synthesis and Signaling During the Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    7. Characterization of Hair Follicle Antigens Targeted by the Anti-Hair Follicle Immune Response Journal of Investigative Dermatology Symposium Proceedings · 2003

    Related research 1

    1. Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata British Journal of Dermatology · 2011