Endogenous Retinoids in the Pathogenesis of Alopecia Areata

    September 2012 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    F. Jason Duncan, Kathleen A. Silva, Claudia Johnson … Helen B. Everts
    Studysummary This study suggests that vitamin A influences the immune response and hair cycle, affecting the progression of alopecia areata in mouse models.
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    Research cited in this study 19

    1. Endogenous Retinoids in the Hair Follicle and Sebaceous Gland Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2011
    2. Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures Genomics · 2010
    3. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    4. Phase I/II Randomized Bilateral Half-Head Comparison of Topical Bexarotene 1% Gel for Alopecia Areata Journal of the American Academy of Dermatology · 2009
    5. Treatment Strategies for Alopecia Expert Opinion on Pharmacotherapy · 2009
    6. Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin Journal of biological chemistry/˜The œJournal of biological chemistry · 2008
    7. Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model ˜The œAmerican journal of pathology · 2008
    8. Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models KARGER eBooks · 2008
    9. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    10. Immunolocalization of Enzymes, Binding Proteins, and Receptors Sufficient for Retinoic Acid Synthesis and Signaling During the Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007
    11. Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2005
    12. Restoration of Hair Growth in Mice with an Alopecia Areata-Like Disease Using Topical Anthralin Experimental Dermatology · 2004
    13. Interleukin-10-Deficient Mice Are Less Susceptible to the Induction of Alopecia Areata Journal of Investigative Dermatology · 2002
    14. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002
    15. Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata Journal of Investigative Dermatology · 2002
    16. Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    17. Comparison of Alopecia Areata in Human and Nonhuman Mammalian Species Pathobiology · 1998
    18. Topical Tretinoin as an Adjunctive Therapy with Intralesional Triamcinolone Acetonide for Alopecia Areata: Clinical Experience in Northern Saudi Arabia International Journal of Dermatology · 1997
    19. Alopecia Areata in Aging C3H/HeJ Mice Journal of Investigative Dermatology · 1994

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