140 citations
,
October 2008 in “Nature Genetics”
212 citations
,
September 2008 in “Journal of The American Academy of Dermatology” This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
74 citations
,
July 2008 in “Dermatologic therapy” This review discusses histopathologic findings in diagnosing primary cicatricial alopecias and emphasizes the importance of correlating histology with clinical presentation for accurate diagnosis; it reports no new results.
90 citations
,
July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
112 citations
,
July 2008 in “Dermatologic Therapy” This review outlines the diagnosis and management of folliculitis decalvans, an inflammatory scalp disorder, and highlights Staphylococcus aureus and immune response deficiencies as key factors in its development.
98 citations
,
May 2008 in “British Journal of Dermatology” This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.
91 citations
,
November 2007 in “Archives of Dermatology” In this study, smoking status and intensity were significantly associated with moderate or severe androgenetic alopecia among Asian men, after accounting for age and family history.
142 citations
,
August 2007 in “Journal of The American Academy of Dermatology” This study found that a new 5% minoxidil foam formulation significantly increased hair counts and improved hair loss condition in men with androgenetic alopecia over 16 weeks compared to placebo.
113 citations
,
May 2007 in “Journal of the American Academy of Dermatology” This study suggests that tetracycline may be more effective for treating lichen planopilaris than previously thought, alongside topical high-potency and intralesional corticosteroids.
43 citations
,
January 2007 in “Gynecological Endocrinology” This study found that 9 out of 12 women with acne or alopecia showed subjective improvement with finasteride treatment despite having normal free testosterone levels, suggesting a potential role of 5alpha-reductase activity.
89 citations
,
December 2006 in “Lancet Oncology” In this study, 1 mg/day finasteride lowered serum PSA concentration in men aged 40–60, suggesting that PSA adjustment recommendations for prostate cancer screening using 5 mg/day finasteride should also apply to this lower dose for hair loss treatment.
215 citations
,
November 2006 in “Journal of The American Academy of Dermatology” This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.
100 citations
,
July 2006 in “British Journal of Dermatology” This study found that intralesional triamcinolone acetonide injections using a needleless injector led to rapid hair regrowth in patients with limited alopecia areata, while lasting growth was rare in alopecia totalis.
108 citations
,
March 2006 in “Archives of Dermatology” This study observed that 62% of premenopausal women with female pattern hair loss reported improvement when treated with oral finasteride and an oral contraceptive containing drospirenone and ethinyl estradiol.
97 citations
,
January 2006 in “Dermatology” This study found that intramuscular triamcinolone acetonide or pulse therapy effectively treats alopecia areata with manageable side effects, but further strategies are needed to reduce relapse rates.
31 citations
,
October 2005 in “British Journal of Dermatology” This study found that sebum excretion is not increased in women with female pattern hair loss, suggesting nonandrogenic factors may contribute to hair loss in some women without hirsutism.
23 citations
,
October 2005 in “Dermatologic Surgery” This study found that finasteride 1 mg daily, taken before and after hair transplant surgery, significantly improved scalp hair coverage and density in men with androgenetic alopecia compared to placebo.
123 citations
,
August 2005 in “Journal of the European Academy of Dermatology and Venereology” In this study, the researchers observed that treatment with intralesional and topical corticosteroids, finasteride, and minoxidil may stop the progression of frontal fibrosing alopecia in postmenopausal and premenopausal women.
195 citations
,
June 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.
179 citations
,
December 2004 in “Journal of The American Academy of Dermatology” This study observed that frontal fibrosing alopecia in postmenopausal women involves selective follicular inflammation, and finasteride treatment may slow disease progression, suggesting a potential androgen-related component.
219 citations
,
March 2004 in “Journal of The American Academy of Dermatology” In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.
397 citations
,
February 2004 in “British Journal of Dermatology” This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
71 citations
,
January 2004 in “Dermatology” This study found that oral finasteride was more effective than 5% topical minoxidil in treating mild to severe androgenetic alopecia in males, with both treatments deemed effective and safe over 12 months.
182 citations
,
October 2003 in “British Journal of Dermatology” These guidelines for alopecia areata management, prepared by the British Association of Dermatologists, provide evidence-based treatment recommendations and insights into the condition's epidemiology, diagnosis, and investigation.
14 citations
,
September 2003 in “Archives of Dermatology” This abstract provides no new data or findings as it is a placeholder text rather than a research summary.
66 citations
,
July 2003 in “International Journal of Dermatology” This study found that betamethasone valerate foam was more effective and well-tolerated than betamethasone dipropionate lotion in treating mild-to-moderate alopecia areata, with higher hair regrowth rates observed.
146 citations
,
July 2003 in “Journal of the American Academy of Dermatology” In this study, clobetasol propionate 0.05% ointment was found to induce hair regrowth in 28.5% of patients with severe alopecia areata under occlusive conditions, though long-term benefit was limited to 17.8%.
62 citations
,
January 2003 in “Dermatology” This review suggests that androgenetic alopecia may be exacerbated by exposure to ultraviolet radiation and proposes considering it as a photoaggravated condition requiring photoprotection.
30 citations
,
October 2002 in “Journal of The American Academy of Dermatology” Use "female pattern hair loss" term, finasteride may help, more research needed.
149 citations
,
June 2002 in “British Journal of Dermatology” Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.
123 citations
,
February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
239 citations
,
November 2000 in “Journal of The American Academy of Dermatology” In this study, finasteride 1 mg/day for 12 months did not improve hair growth or slow hair thinning in postmenopausal women with androgenetic alopecia compared to placebo.
115 citations
,
November 1999 in “Journal of The American Academy of Dermatology” In this study, men using 2% and 5% minoxidil solutions experienced a significant increase in hair weight for 96 weeks compared to placebo, with effects diminishing after treatment cessation.
187 citations
,
June 1999 in “Journal of The American Academy of Dermatology” This study reported that finasteride 1 mg/day significantly increased hair growth and slowed hair loss in men with frontal scalp hair thinning over one year, and these benefits continued or improved in the second year.
226 citations
,
February 1999 in “British Journal of Dermatology” This study reported that a treatment regimen of oral rifampicin and clindamycin for 10 weeks effectively managed folliculitis decalvans, with most patients experiencing no recurrence after one or multiple courses.
132 citations
,
November 1998 in “Journal of the American Academy of Dermatology” This review evaluates the efficacy and safety of topical sensitizers in treating alopecia areata but reports no new clinical findings.
581 citations
,
October 1998 in “Journal of The American Academy of Dermatology” In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.
44 citations
,
January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia experienced severe facial and limb hypertrichosis after using 5% topical minoxidil, which resolved after discontinuing the treatment.
30 citations
,
November 1996 in “Archives of Dermatology” This report describes cases of increased hair loss and scalp sunburns in patients using 3% minoxidil and 0.01% tretinoin, suggesting caution with tretinoin use on sunny days.
105 citations
,
December 1995 in “British journal of dermatology/British journal of dermatology, Supplement” This retrospective study concluded that PUVA treatment is generally ineffective for alopecia areata, with low effective success rates for partialis, totalis, and universalis types.
33 citations
,
July 1992 in “Journal of Investigative Dermatology” Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.
46 citations
,
June 1990 in “Archives of dermatology” In this study, combination therapy with 5% minoxidil and 0.5% anthralin showed some cosmetic improvement in 11% of patients with severe treatment-resistant alopecia areata, with hair regrowth starting by week 12.
70 citations
,
April 1990 in “Journal of The American Academy of Dermatology” Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.
38 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
109 citations
,
November 1987 in “Archives of dermatology” In this study, 0.5%-1.0% anthralin cream led to a cosmetic response in 25% of patients with severe alopecia areata, despite common side effects like pruritus and erythema.