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GlossaryPsoralen and Ultraviolet A Therapy (Photochemotherapy)

combines a drug and UVA light to treat skin conditions

Psoralen and Ultraviolet A Therapy (PUVA) is a type of photochemotherapy used to treat various skin conditions, including psoriasis, vitiligo, and certain types of eczema. The treatment involves taking a drug called psoralen, which makes the skin more sensitive to ultraviolet A (UVA) light, followed by exposure to UVA light. This combination helps to slow down the excessive growth of skin cells and can reduce symptoms like itching and inflammation.

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research Photochemotherapy and Alopecia Areata

10 citations, May 1983 in “International Journal of Dermatology”

Some people with severe hair loss saw hair regrowth after a specific light and drug treatment.

research Topical Photochemotherapy for Alopecia Areata

63 citations, April 1985 in “Journal of the American Academy of Dermatology”

Topical PUVA can cause temporary hair regrowth in some alopecia areata patients but doesn't change the long-term outcome.

research Targeted Photochemotherapy in Alopecia Areata

3 citations, October 2013 in “Photodermatology Photoimmunology & Photomedicine”

The treatment is a safe and effective option for hair regrowth in patchy alopecia areata.

research The Liver Monooxygenase System in Patients with Alopecia

September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.

research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012

218 citations, April 2012 in “British Journal of Dermatology”

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

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