The Liver Monooxygenase System in Patients with Alopecia
TLDR Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.
The study titled "The liver monoxygenase system in patients with alopecia" aimed to investigate the role of the monoxygenase system in the pathogenesis of alopecia. It included 43 patients with different types of alopecia, classified by age of onset and duration. The study found that the antipyrine half-life in alopecic patients exceeded by 32% compared to healthy controls, indicating an inhibited monoxygenase system in alopecia patients. The activity of the monoxygenase system correlated with the duration and type of alopecia, with the lowest activity observed in patients with alopecia universalis compared to those with alopecia areata. A new treatment method combining photochemotherapy and monoxygenase system inducers was utilized.
