TLDR Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.
The study titled "The liver monoxygenase system in patients with alopecia" aimed to investigate the role of the monoxygenase system in the pathogenesis of alopecia. It included 43 patients with different types of alopecia, classified by age of onset and duration. The study found that the antipyrine half-life in alopecic patients exceeded by 32% compared to healthy controls, indicating an inhibited monoxygenase system in alopecia patients. The activity of the monoxygenase system correlated with the duration and type of alopecia, with the lowest activity observed in patients with alopecia universalis compared to those with alopecia areata. A new treatment method combining photochemotherapy and monoxygenase system inducers was utilized.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Psychological factors play a significant role in developing alopecia areata.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Spironolactone is more effective than finasteride in treating excessive hair growth in women.
2 citations,
April 2022 in “Genes” The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.