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    GlossaryMethotrexate

    inhibits cell growth by blocking folic acid metabolism

    Methotrexate (MTX) is a medication commonly used to treat certain types of cancer, autoimmune diseases like rheumatoid arthritis, and severe psoriasis. It works by inhibiting the metabolism of folic acid, which is necessary for the rapid growth of cells, thereby slowing down the proliferation of cancer cells and modulating the immune system.

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      The Pharmacology of Methotrexate

      research The Pharmacology of Methotrexate

      155 citations, August 1991 in “Journal of The American Academy of Dermatology”
      Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
      Methotrexate in the Treatment of Steroid-Dependent Asthma

      research Methotrexate in the Treatment of Steroid-Dependent Asthma

      80 citations, August 1991 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
      Methotrexate in Dermatology

      research Methotrexate in Dermatology

      77 citations, July 2007 in “Dermatologic Therapy”
      Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.
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