TLDR Alopecia Areata is treated with drugs and therapies to reduce inflammation and immune response.
Alopecia Areata (AA) is an autoimmune disease where T lymphocytes attack hair follicles, leading to sudden hair loss. The treatment aims to modulate the inflammatory process around hair follicles through immunosuppressants and immunomodulatory agents. Factors such as genetics, autoantigens, immune cell activity, and stress contribute to AA's pathogenesis. Therapeutic options include corticosteroid injections, minoxidil, immunotherapies, photochemotherapy, calcineurin inhibitors, methotrexate, sulfasalazine, azathioprine, laser therapy, PRP therapy, and stem cell therapy.
15 citations
,
February 2020 in “Experimental Dermatology” The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.
January 2020 in “Archives of Medicine and Health Sciences” Certain immune molecules and stress affect hair loss, and while genes play a role, more research is needed to fully understand and treat it.
45 citations
,
May 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
14 citations
,
January 2019 in “PubMed” Vitamin D might be involved in the development of alopecia areata and could help in its treatment.
1 citations
,
January 2018 in “Skin appendage disorders” The complement system might be involved in the development of alopecia areata and could lead to new treatments.
17 citations
,
July 1994 in “Journal of Dermatological Science” The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.