Does Complement Have a Role in the Pathogenesis of Alopecia Areata?

    January 2018 in “ Skin appendage disorders ”
    Margit Juhász, Natasha Atanaskova Mesinkovska
    Studysummary This review discusses the role of the complement pathway in alopecia areata and reports no new clinical results; the authors suggest that targeting this pathway could offer treatment options.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 5

    1. Alopecia Areata: What’s New in Epidemiology, Pathogenesis, Diagnosis, and Therapeutic Options? Journal of dermatological science · 2016
    2. T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus Experimental dermatology · 2016
    3. Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study International Journal of Dermatology · 2006
    4. Failure of Passive Transfer of Serum From Patients With Alopecia Areata and Alopecia Universalis to Inhibit Hair Growth in Transplants of Human Scalp Skin Grafted Onto Nude Mice British Journal of Dermatology · 1992
    5. Immunologic Studies in Patients With Alopecia Areata Archives of Dermatology · 1981