Vitiligo: A Comprehensive Overview

    August 2011 in “ Journal of the American Academy of Dermatology ”
    Ali Alikhan, Lesley M. Felsten, Meaghan Daly, Vesna Petronic‐Rosic
    Image of study
    TLDR Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
    The document from 2011 provides a comprehensive overview of vitiligo, an acquired pigmentary disorder with an unknown cause, characterized by the development of white macules due to the loss of melanocytes. The prevalence of vitiligo is about 1% in the United States and Europe, with global rates varying from less than 0.1% to over 8%. The condition shows a higher recorded incidence in women, possibly due to their greater concern for cosmetic issues. Vitiligo commonly begins before the age of 20, and while late-onset can occur, it is rare and may indicate other associated diseases like thyroid dysfunction, rheumatoid arthritis, diabetes mellitus, and alopecia areata. Generalized vitiligo, which often affects the face and acral regions, is the most common form. The progression of vitiligo is unpredictable, and treatment responses vary. The disorder can lead to significant psychological distress, reduced quality of life, and a higher risk of psychiatric issues. The document details the clinical features, histopathological findings, and proposes several pathogenesis hypotheses based on research available up to that time.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 7 results

      community 1 Month Topical Minoxidil Only

      in Progress Pictures  72 upvotes 1 year ago
      The conclusion of the conversation is that the user plans to use topical minoxidil, ketoconazole shampoo, and a derma stamp for hair loss treatment. They also plan to start using finasteride in the next 2 months. Other users suggest using finasteride and a hair transplant for better results. The user appreciates the feedback and will continue posting progress.

      community One full year of treatment before and after

      in Progress Pictures  19 upvotes 3 months ago
      A user shared their one-year progress with hair loss treatment, using topical minoxidil, 2% keto shampoo, microneedling, and finasteride. They plan to start dutasteride and are considering switching to oral minoxidil.

      community Fighting Hair loss AND Grey Hair

      in Treatment  18 upvotes 2 years ago
      The user is treating hair loss with topical Minoxidil, Finasteride, RU58841, microneedling, and Ketoconazole. For grey hair, they use L-Cysteine, L-Methionine, and PABA, and have noticed some re-pigmentation.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 7 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community fin 0.5 mg everday 6 months update

      in Finasteride/Dutasteride  28 upvotes 1 year ago
      The post discusses the experiences of individuals with diffuse hair thinning using finasteride, with many reporting no improvement or worsening conditions after 6 months. Various suggestions include persisting with the treatment, checking for underlying conditions, adding minoxidil for volume, adjusting dosage, and considering other potential causes like autoimmune responses and inflammation.

    Similar Research

    5 / 1000+ results