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GlossaryImmunostaining (immunohistochemical staining)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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Investigating the Role of Various Extracellular Matrix in Androgenetic Alopecia: Insights from Immunostaining and Quantitative Analysis - A Pilot Study

research Investigating the Role of Various Extracellular Matrix in Androgenetic Alopecia: Insights from Immunostaining and Quantitative Analysis - A Pilot Study

October 2024 in “Dermatologica Sinica”

ECM changes may play a role in hair loss, with differences between males and females.

research Phenotypic Analysis of T-Cells in Extensive Alopecia Areata Scalp Suggests Partial Tolerance

21 citations, December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

research Expression of COX-2 and Bcl-2 in 50 Patients of Lichen Planus

April 2020 in “International journal of clinical and diagnostic pathology”

COX-2 and Bcl-2 proteins are involved in Lichen Planus.

research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain

May 2024 in “Scientific Reports”

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

research Claudin-1 and Claudin-3 Maintain Proper Hair Follicle Structure and Regulate Telogen Effluvium

April 2018 in “Journal of Investigative Dermatology”

Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 680 upvotes 4 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Another clueless guy fearmongering and spreading misinformation

in Chat 251 upvotes 1 year ago

The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.