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GlossaryImmunostaining (immunohistochemical staining)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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research ABO Blood Grouping of Non-Medullated Scalp Hair Using Immunohistochemical Staining

January 2010 in “Nihon Hou Kagaku Gijutsu Gakkaishi”

The modified staining method can determine the ABO blood group of hair samples accurately.

research Ultrastructural and Immunohistochemical Characteristics of Telocytes in Human Scalp Tissue

14 citations , February 2020 in “Scientific reports”

Telocytes in the scalp may help with skin regeneration and maintenance.

research Effects of Cyclosporine A on Clinical and Histologic Abnormalities in Dogs with Sebaceous Adenitis

34 citations , January 2005 in “Journal of the American Veterinary Medical Association”

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing

research Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing

32 citations , March 2014 in “PLOS ONE”

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

research Phenotypic Variability Associated with WNT10A Nonsense Mutations

28 citations , February 2010 in “British journal of dermatology/British journal of dermatology, Supplement”

WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 410 upvotes 5 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 679 upvotes 10 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Another clueless guy fearmongering and spreading misinformation

in Chat 251 upvotes 1 year ago

The conversation discusses hair loss treatments, with some users advocating for finasteride and minoxidil, while others express concerns about potential side effects of finasteride. A social media influencer is criticized for promoting scalp massages and minoxidil over finasteride, which some believe is misinformation.