Vitamin D and Alopecia Areata: Possible Roles in Pathogenesis and Potential Implications for Therapy

    January 2019 in “ PubMed ”
    Xiran Lin, Xianmin Meng, Zhiqi Song
    Studysummary This review examines the potential roles of vitamin D in the pathogenesis of alopecia areata and suggests that vitamin D analogs like calcipotriol may have therapeutic potential.
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    Research cited in this study 37

    1. Regulatory T-Cells in Alopecia Areata Journal of cutaneous pathology · 2019
    2. The Use of Janus Kinase Inhibitors in Alopecia Areata: A Review of the Literature Journal of cutaneous medicine and surgery · 2019
    3. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    4. Evaluation of the Efficacy of Transdermal Drug Delivery of Calcipotriol Plus Betamethasone Versus Tacrolimus in the Treatment of Vitiligo Journal of Cosmetic Dermatology · 2018
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    6. Increased Prevalence of Vitamin D Deficiency in Patients with Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2018
    7. Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2017
    8. Correlation of Vitamin D and Vitamin D Receptor Expression in Patients with Alopecia Areata: A Clinical Paradigm International Journal of Dermatology · 2017
    9. Vitamin D Deficiency in Patients With Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2017
    10. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    11. The Role of Vitamin D in Non-Scarring Alopecia International Journal of Molecular Sciences · 2017
    12. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    13. Serum Vitamin D Level Is Related to Disease Severity in Pediatric Alopecia Areata Journal of cosmetic dermatology · 2017
    14. Efficacy and Safety of Topical Calcipotriol in Management of Alopecia Areata: A Pilot Study Dermatologic Therapy · 2017
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    18. Estimated Serum Vitamin D Status, Vitamin D Intake, and Risk of Incident Alopecia Areata Among US Women Archives of Dermatological Research · 2016
    19. CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016
    20. Understanding Autoimmunity of Vitiligo and Alopecia Areata Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics · 2016
    21. Assessment of Vitamin D Receptors in Alopecia Areata and Androgenetic Alopecia Journal of Cosmetic Dermatology · 2016
    22. The Transient Role of Calcium and Vitamin D During the Developmental Hair Follicle Cycle Journal of Investigative Dermatology · 2016
    23. Altered Expression of Intracellular Toll-Like Receptors in Peripheral Blood Mononuclear Cells from Patients with Alopecia Areata BBA clinical · 2016
    24. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling Cellular physiology and biochemistry · 2016
    25. The Role of Lymphocytes in the Development and Treatment of Alopecia Areata Expert Review of Clinical Immunology · 2015
    26. The Vitamin D Receptor Functions as a Transcription Regulator in the Absence of 1,25-Dihydroxyvitamin D3 The Journal of Steroid Biochemistry and Molecular Biology · 2015
    27. Imbalance of T-Helper 17 and Regulatory T Cells in Patients with Alopecia Areata The Journal of Dermatology · 2015
    28. Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study PubMed · 2015
    29. Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata EBioMedicine · 2015
    30. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    31. Vitamin D Deficiency in Alopecia Areata British journal of dermatology/British journal of dermatology, Supplement · 2014
    32. Oxidative Stress in Alopecia Areata: A Case-Control Study American Journal of Clinical Dermatology · 2013
    33. Reduced Level of 25-Hydroxyvitamin D in Chronic/Relapsing Alopecia Areata Dermato-endocrinology · 2013
    34. Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata Clinical and Developmental Immunology · 2013
    35. Genetic Basis of Alopecia Areata Dermatologic clinics · 2012
    36. Successful Treatment of Alopecia Areata with Topical Calcipotriol Annals of dermatology/Annals of Dermatology · 2012
    37. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010

    Related research 4

    1. Role of Vitamin D in Hair Loss: A Short Review Journal of Cosmetic Dermatology · 2021
    2. Vitamin D and Alopecia Areata: Possible Roles in Pathogenesis and Potential Implications for Therapy PubMed · 2019
    3. The Role of Vitamin D in Non-Scarring Alopecia International Journal of Molecular Sciences · 2017
    4. Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata Journal of Clinical Investigation · 2007