Vitamin D and Alopecia Areata: Possible Roles in Pathogenesis and Potential Implications for Therapy

The 2019 document investigated the potential roles of Vitamin D in the development and treatment of alopecia areata. It found that Vitamin D deficiency was common in patients with this condition, suggesting it may play a role in its onset. The document also reported successful treatment of alopecia areata with topical calcipotriol, a Vitamin D analogue, and discussed Vitamin D's ability to regulate T cells, which are involved in the disease's pathogenesis. However, it also noted unsuccessful attempts to treat alopecia totalis with calcipotriol. The document concluded that Vitamin D could potentially be used as a therapeutic agent for alopecia areata, but emphasized the need for further research to confirm these findings.