Estimated Serum Vitamin D Status, Vitamin D Intake, and Risk of Incident Alopecia Areata Among US Women

September 2016 in “ Archives of Dermatological Research ”

Jordan M. Thompson, Tricia Li, Min Kyung Park, Abrar A. Qureshi, Eunyoung Cho

alopecia areata vitamin D serum vitamin D Nurses’ Health Study AA

TLDR Vitamin D levels do not affect the risk of developing alopecia areata.

In a study of 55,929 women from the Nurses’ Health Study over 12 years, researchers found no significant association between vitamin D levels and the risk of developing alopecia areata (AA). Among 133 identified cases of AA, the age-adjusted hazard ratio for the highest versus lowest quartiles of serum vitamin D score was 0.94, and the multivariate hazard ratio was 1.08. These results did not support a preventive role for vitamin D in the risk of developing AA.

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Research cited in this study

11 / 11 results

research Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study

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research Vitamin D Deficiency in Alopecia Areata

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A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

research Vitamin D Concentrations Are Decreased in Patients with Alopecia Areata

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People with Alopecia Areata have lower vitamin D levels.

research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity

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research Vitamin D Receptor Gene Polymorphisms Are Not Associated With Alopecia Areata

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research Lack of Association Between Vitamin D Receptor FokI Polymorphism and Alopecia Areata

10 citations , September 2004 in “PubMed”

Vitamin D receptor FokI gene variation is not linked to alopecia areata.

research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth

180 citations , January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D Receptor is crucial for normal skin and hair growth.

research Metabolic And Cellular Analysis Of Alopecia In Vitamin D Receptor Knockout Mice

137 citations , April 2001 in “Journal of Clinical Investigation”

Alopecia in these mice is caused by defective hair cycle communication due to missing vitamin D receptor function, not vitamin D levels.

research Topical Use of Calcipotriol Does Not Potentiate Squaric Acid Dibutylester Effectiveness in the Treatment of Alopecia Areata

5 citations , January 1995 in “Journal of Dermatological Treatment”

Calcipotriol does not improve the effectiveness of squaric acid dibutylester in treating alopecia areata.

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