TLDR Vitamin D receptor gene variations are not linked to alopecia areata.
The study investigated the association between vitamin D receptor (VDR) gene polymorphisms (BsmI, ApaI, and TaqI) and alopecia areata (AA) by genotyping 32 patients with AA and 27 healthy controls. The allele and genotype frequencies for the B, A, and T polymorphisms showed no statistically significant differences between the patient and control groups. The findings suggested that VDR gene polymorphisms were not associated with alopecia areata.
180 citations,
January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is crucial for normal skin and hair growth.
10 citations,
January 2019 in “Advances in Clinical and Experimental Medicine” Certain variations in the vitamin D receptor gene are linked to an increased risk of polycystic ovary syndrome.
3 citations,
January 2020 in “Indian Journal of Dermatology” Certain gene variations in the Vitamin D Receptor are linked to higher risk of female hair loss.
36 citations,
January 2017 in “Journal of Obstetrics and Gynaecology Research” The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.
1308 citations,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
