Analysis of Vitamin D Receptor Gene Polymorphisms in Alopecia Areata
January 2017
in “
The Annals of Clinical and Analytical Medicine
”
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Studysummary In this study, researchers found no significant association between VDR gene polymorphisms and the susceptibility to alopecia areata, suggesting that these genetic variations may not play a role in the disease's development.
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The study aimed to investigate the role of Vitamin D receptor (VDR) gene polymorphisms in the development of alopecia areata (AA), a disease characterized by hair loss and affecting 1%-2% of the population. The research involved 198 patients with AA and 167 controls, analyzing the frequency of VDR gene polymorphisms using PCR and RFLP methods. The results showed no significant association between the VDR gene polymorphisms (BsmI, ApaI, TaqI) and AA, suggesting that these polymorphisms did not play a role in genetic susceptibility to the disease.
