Reduced Level of 25-Hydroxyvitamin D in Chronic/Relapsing Alopecia Areata

April 2013 in “ Dermato-endocrinology ”

Francesco Domenico D’Ovidio, Margherita Vessio, Francesco Domenico D’Ovidio

25-hydroxyvitamin D Alopecia Areata vitamin D deficiency Parathyroid Hormone PTH DHEA-S vitamin D AA

TLDR People with chronic Alopecia Areata often have lower vitamin D levels.

The study, conducted from October 2010 to March 2012, included 156 patients with chronic relapsing/remitting Alopecia Areata (AA) and 148 control individuals. It found that patients with AA had a significantly higher rate of vitamin D deficiency, with 42.4% having levels below 20 ng/ml, compared to 29.5% in the control group. Additionally, there was a significant increase in Parathyroid Hormone (PTH) levels among the AA patients, indicating a true deficiency in vitamin D. No correlation was found between vitamin D and DHEA-S levels, suggesting they are independent risk factors for AA. The study concluded that vitamin D deficiency is more common in patients with chronic relapsing/remitting AA, and there is an inverse correlation between vitamin D and PTH levels, which may have implications for the treatment of AA.

View this study on europepmc.org →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Successful Treatment of Alopecia Areata with Topical Calcipotriol

51 citations, January 2012 in “Annals of dermatology/Annals of Dermatology”

A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

research Hyposecretion of the Adrenal Androgen Dehydroepiandrosterone Sulfate (DHEA-S) in the Majority of Alopecia Areata Patients: Is It a Primitive and Pathogenic Perturbation of the Hypothalamic-Pituitary-Adrenal Axis?

3 citations, January 2011 in “International journal of trichology”

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

Related Research

2 / 2 results

research Serum Vitamin D Level Is Related to Disease Severity in Pediatric Alopecia Areata

28 citations, April 2017 in “Journal of cosmetic dermatology”

Low vitamin D can worsen pediatric alopecia areata.

research Vitamin D Deficiency in Alopecia Areata

105 citations, March 2014 in “British journal of dermatology/British journal of dermatology, Supplement”

Alopecia areata patients often have low vitamin D levels, suggesting they might benefit from vitamin D supplements.

Reduced Level of 25-Hydroxyvitamin D in Chronic/Relapsing Alopecia Areata

Research cited in this study

research Successful Treatment of Alopecia Areata with Topical Calcipotriol

research Hyposecretion of the Adrenal Androgen Dehydroepiandrosterone Sulfate (DHEA-S) in the Majority of Alopecia Areata Patients: Is It a Primitive and Pathogenic Perturbation of the Hypothalamic-Pituitary-Adrenal Axis?

Related Community Posts Join

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

community Iron Overload and Vitamin D Deficiency - Male Hair Loss

community 25-31 recovery makes my hair almost unmanageable.

community 25 Years old. 3 Months on Fin/Min, plus Hair & Nail Vitamins.

community 25 M – progress from July 21 to April 23 [1.25 mg oral fin per day, top min 2x per day]

community 25 months. Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL, fixing vitamin D levels

Related Research

research Serum Vitamin D Level Is Related to Disease Severity in Pediatric Alopecia Areata

research Vitamin D Deficiency in Alopecia Areata