Serum Vitamin D Level Is Related to Disease Severity in Pediatric Alopecia Areata

April 2017 in “ Journal of cosmetic dermatology ”

Mehmet Ünal, Gülsüm Gönülalan

vitamin D alopecia areata SALT score 25(OH)D disease severity pediatric patients vitamin D deficiency vitamin D supplementation AA children vitamin D supplements

From the encyclopedia

Vitamin D →

vitamin you should probably be taking for general health might also help your hair a little

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Studysummary This study found that while vitamin D deficiency is not the sole cause of alopecia areata, it may worsen the disease, suggesting supplementation could help in pediatric cases.

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The study investigated the relationship between vitamin D levels and disease severity in pediatric alopecia areata (AA). It included 20 pediatric patients with AA and 34 healthy controls. The mean serum 25(OH)D concentration was 15.47±7.66 ng/mL in patients and 11.09±10.53 ng/mL in controls, with no statistically significant difference between the groups (P: .084). However, vitamin D levels were significantly and negatively correlated with the SALT score, number of patches, and disease duration (all P<.001). The study concluded that while vitamin D deficiency is not the sole cause of AA, it can exacerbate the condition, suggesting that vitamin D supplementation might be beneficial in treating pediatric AA.

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Research cited in this study

5 / 5 results

research Vitamin D Deficiency in Alopecia Areata

105 citations , March 2014 in “British journal of dermatology/British journal of dermatology, Supplement”

In this study, patients with alopecia areata were found to have significantly lower serum vitamin D levels compared to those with vitiligo and healthy individuals, with lower levels correlating with increased disease severity.

research Reduced Level of 25-Hydroxyvitamin D in Chronic/Relapsing Alopecia Areata

40 citations , April 2013 in “Dermato-endocrinology”

In this study, researchers observed vitamin D insufficiency in many patients with Alopecia Areata, suggesting its potential role in managing this autoimmune condition.

research Vitamin D Concentrations Are Decreased in Patients with Alopecia Areata

54 citations , January 2012 in “Vitamins & Trace Elements”

This study found significantly lower serum vitamin D concentrations in patients with alopecia areata compared to healthy controls, suggesting that vitamin D deficiency may be a risk factor for this autoimmune hair loss disease.

research Investigative Guidelines for Alopecia Areata

66 citations , May 2011 in “Dermatologic therapy”

This report discusses guidelines for designing alopecia clinical trials that account for variables affecting results, but it presents no new efficacy findings.

research The Preventive Effect of Vitamin D3 on Radiation-Induced Hair Toxicity in a Rat Model

14 citations , November 2005 in “Life sciences”

This study indicates that vitamin D3 administration may protect rat hair follicles from radiation-induced damage, as evidenced by maintained follicle numbers and increased Vitamin D receptor activity in treated skin.