Serum Vitamin D Level Is Related to Disease Severity in Pediatric Alopecia Areata

    April 2017 in “ Journal of cosmetic dermatology
    Mehmet Ünal, Gülsüm Gönülalan
    TLDR Low vitamin D can worsen pediatric alopecia areata.
    The study investigated the relationship between vitamin D levels and disease severity in pediatric alopecia areata (AA). It included 20 pediatric patients with AA and 34 healthy controls. The mean serum 25(OH)D concentration was 15.47±7.66 ng/mL in patients and 11.09±10.53 ng/mL in controls, with no statistically significant difference between the groups (P: .084). However, vitamin D levels were significantly and negatively correlated with the SALT score, number of patches, and disease duration (all P<.001). The study concluded that while vitamin D deficiency is not the sole cause of AA, it can exacerbate the condition, suggesting that vitamin D supplementation might be beneficial in treating pediatric AA.
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