TLDR Low vitamin D can worsen pediatric alopecia areata.
The study investigated the relationship between vitamin D levels and disease severity in pediatric alopecia areata (AA). It included 20 pediatric patients with AA and 34 healthy controls. The mean serum 25(OH)D concentration was 15.47±7.66 ng/mL in patients and 11.09±10.53 ng/mL in controls, with no statistically significant difference between the groups (P: .084). However, vitamin D levels were significantly and negatively correlated with the SALT score, number of patches, and disease duration (all P<.001). The study concluded that while vitamin D deficiency is not the sole cause of AA, it can exacerbate the condition, suggesting that vitamin D supplementation might be beneficial in treating pediatric AA.
105 citations,
March 2014 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata patients often have low vitamin D levels, suggesting they might benefit from vitamin D supplements.
40 citations,
April 2013 in “Dermato-endocrinology” People with chronic Alopecia Areata often have lower vitamin D levels.
66 citations,
May 2011 in “Dermatologic therapy” Guidelines help design better trials to compare alopecia areata treatments.
14 citations,
November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations,
November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
110 citations,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
