An Investigation of Vitamin D Status in Alopecia Areata

June 2018 in “ Clinical and Experimental Medicine ”

Venkata Krishna Vamsi Gade, Archana Mony, Malathi Munisamy, Laxmisha Chandrashekar, Medha Rajappa

vitamin D alopecia areata serum 25-hydroxy vitamin D high-sensitivity C-reactive protein systemic inflammation vitamin D deficiency pathogenesis vitamin D supplementation AA hs-CRP

TLDR People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.

The study from June 2018 examined the link between vitamin D deficiency and alopecia areata (AA), involving 45 AA patients and 45 healthy controls. It found that AA patients had significantly lower serum 25-hydroxy vitamin D levels and higher high-sensitivity C-reactive protein (hs-CRP) levels, indicating systemic inflammation. There was a significant negative correlation between vitamin D levels and AA severity, and a positive correlation between hs-CRP levels and severity. These results suggest that vitamin D deficiency may play a role in the pathogenesis of AA and that vitamin D supplementation could potentially alleviate symptoms and promote remission in AA patients. However, further research is needed to confirm these findings.

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