Alopecia Areata After HLA-Identical Bone Marrow Transplant from an Affected Sibling Donor

    January 2014 in “ Bone marrow transplantation
    Syed Maaz Nadeem, Sharon R. Hymes, Partow Kebriaei, Lynne V. Abruzzo, Jonathan L. Curry, Madeleine Duvic
    TLDR Alopecia areata can be transferred through stem cell transplants from affected siblings.
    The document reported cases of alopecia areata developing in patients after receiving allogeneic stem cell transplants (allo-SCT) from HLA-identical siblings who also had alopecia areata. Specifically, a 48-year-old man with chronic myeloid leukemia (CML) developed alopecia areata 15 months post-transplant, and a 55-year-old woman with acute myeloid leukemia (AML) developed the condition 16 months post-transplant. This suggested that alopecia areata could be transferred via T cells in the transplant from affected donors.
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