Identifying Key Components and Therapeutic Targets of the Immune System in Hidradenitis Suppurativa with an Emphasis on Neutrophils
September 2020
in “
British journal of dermatology/British journal of dermatology, Supplement
”
hidradenitis suppurativa neutrophils hair follicle unit bacterial components complement pathway anaphylatoxins C3a C5a tumor necrosis factor-alpha interleukins IL-17 IL-8 CXCL8 IL-36 IL-1 lipocalin-2 leukotriene B4 platelet-activating factor kallikreins matrix metalloproteinases myeloperoxidase inhibitors HS TNF-alpha MMPs
Studysummary This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.
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