learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity April 2018 in “Journal of Investigative Dermatology” IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Cellular and Molecular Mechanisms of Repair in Acute and Chronic Wound Healing 908 citations, July 2015 in “British Journal of Dermatology” Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
research Self-Organization Process in Newborn Skin Organoid Formation Inspires Strategy to Restore Hair Regeneration of Adult Cells 92 citations, August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate 57 citations, March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia 25 citations, June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
community Comprehensive Microneedling Guide in Microneedling 288 upvotes 2 years ago Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.