Matrix Remodelling and MMP Expression/Activation Are Associated with Hidradenitis Suppurativa Skin Inflammation

    March 2019 in “ Experimental Dermatology ”
    J. Sanchez, Sébastien Le Jan, C. Muller … Frank Antonicelli
    Studysummary This study suggests that in hidradenitis suppurativa, MMP-induced matrix alterations may contribute to inflammation by releasing active peptides and inflammatory factors in the extracellular matrix.
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    Research cited in this study 1

    1. Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology Experimental dermatology · 2013