Pharmacotherapy for Keloids and Hypertrophic Scars

The review article "Pharmacotherapy for Keloids and Hypertrophic Scars" highlights the challenges in treating these conditions, emphasizing that combination therapies are more effective than monotherapies. Key treatments include ACE inhibitors, tranilast, antisense drugs, interferons, calcium antagonists, chemotherapeutics, enzymes, vitamins, immunomodulators, monoclonal antibodies, botulinum toxin A, pentoxifylline, plant-based compounds, statins, and steroids. These treatments aim to reduce fibroblast proliferation, collagen production, and inflammation, promote wound healing, and induce fibroblast apoptosis. The review underscores the importance of personalized treatment plans and further research to optimize these therapies.