Hyaluronic Acid, a Promising Skin Rejuvenating Biomedicine: A Review of Recent Updates and Pre-Clinical and Clinical Investigations on Cosmetic and Nutricosmetic Effects

    December 2018 in “ International journal of biological macromolecules ”
    Syed Nasir Abbas Bukhari, Nur Liyana Roswandi, Muhammad Waqas, Haroon Habib, Fahad Hussain, Shahzeb Khan, Muhammad Sohail, Nor Amlizan Ramli, Hnin Ei Thu, Zahid Hussain
    TLDR Hyaluronic acid is effective for skin rejuvenation and should be a key ingredient in cosmetic products.
    The review highlighted the multifaceted role of hyaluronic acid (HA) in skin rejuvenation, emphasizing its efficacy in treating wrinkles, nasolabial folds, and skin aging through various formulations like gels, creams, and injections. Clinical studies, including one with 158 patients, demonstrated significant improvements in skin appearance and soft tissue augmentation. HA's ability to stimulate collagen synthesis, improve skin hydration, and enhance skin elasticity and tightness was well-documented. The review concluded that HA, alone or combined with other agents, showed promising cosmetic and nutricosmetic effects, making it a prime component in skincare products.
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