The Biological Role of Platelet Derivatives in Regenerative Aesthetics

    Loamy Santos, Giselle Lobo Lana, Gabriel Silva Santos, Silvia Beatriz Coutinho Visoni, Rayssa Junqueira Brigagão, Napoliane Santos, Rafaela Sobreiro, Abdülkadir Reís, Bruno Rodrigues, Sabrina Ferrari, Cláudia Herrera Tambeli, José Fábio Lana
    TLDR Platelet-derived products help regenerate tissue and are used in various skin and hair treatments.
    The document reviews the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in regenerative aesthetics, focusing on their roles in hair regrowth, skin rejuvenation, and treating conditions like androgenetic alopecia and acne scars. PRP enhances cell proliferation, differentiation, and collagen production, showing significant improvements in hair density, skin texture, and overall appearance across multiple studies. Combining PRP with treatments like microneedling or fractional CO2 laser further enhances efficacy. Despite promising results, the lack of standardized preparation protocols poses challenges, necessitating further research for consistent outcomes. The review underscores PRP's potential as a valuable tool in aesthetic medicine.
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