TLDR Platelet-rich treatments can help improve wound healing and tissue repair.
The document reviews the multifaceted role of platelets in hemostasis, tissue repair, and immune response, and the use of platelet-rich concentrates for therapeutic purposes in clinical settings. It explains that platelets release mediators that coordinate tissue repair and that local application of platelet-rich concentrates and fibrin can enhance wound healing in medicine and dentistry. The review details the preparation methods for platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), which involve centrifugation of blood, with or without anticoagulants, to concentrate platelets. The document acknowledges the potential of PRP and PRF in treating various conditions, including alopecia and skin rejuvenation, but also notes the current limitations due to small study sizes and potential bias, highlighting the need for more standardized and well-designed studies. The authors, E.E.J. and M.H., with contributions from A.B. and P.J., report no external funding or conflicts of interest.
21 citations,
June 2019 in “Dermatologic Surgery” Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.
51 citations,
March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
39 citations,
March 2019 in “Dermatologic Surgery” PRP therapy increases hair density for androgenetic alopecia.
31 citations,
January 2019 in “Journal of Cutaneous Medicine and Surgery” Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.
76 citations,
December 2018 in “Aesthetic Plastic Surgery” Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
113 citations,
July 2015 in “Journal of Cosmetic Dermatology” Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.
July 2024 in “Periodontology 2000” Autologous platelet concentrates show promise in esthetic treatments but need more standardized research.
PRP is a versatile and affordable treatment for improving appearance in the elderly, with patient needs and expectations being important.
1 citations,
January 2021 in “Indian Dermatology Online Journal” PRP can help treat hair loss but needs standardized methods for best results.
Platelet-rich plasma is a promising and cost-effective treatment for hair and skin issues in older adults in India.
August 2021 in “International Journal of Dermatology and Venereology” Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.
Injectable PRF therapy may help with hair growth and skin rejuvenation, but more research is needed.
