Clinical Application of Platelet-Rich Fibrin in Dermatology

    August 2021 in “ International Journal of Dermatology and Venereology ”
    Qing-Yun Wu, Qian Zhang, Fang Fang, Wenbo Bu
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    TLDR Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.
    Platelet-Rich Fibrin (PRF), a second-generation platelet concentrate, has shown potential in dermatology due to its high concentration of growth factors and cytokines. It has been used in the treatment of chronic wounds, androgenic alopecia (AGA), skin rejuvenation, autologous fat transplantation, and vitiligo treatment. PRF has shown to increase the speed of healing in chronic wounds, improve hair density in AGA treatment, and act as a natural filler in skin rejuvenation. In a clinical trial with 25 patients, PRF combined with fat was found to be more effective than fat and Platelet-Rich Plasma (PRP) in facial lipostructure surgery. However, the application of PRF in hair loss management is still in the early stages and requires further evaluation in high-quality randomized controlled trials. The document also highlights the need for a standardized protocol and large-scale studies for PRF treatment.
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      community Hairloss after doing PRF treatment

      in Treatment  2 upvotes 1 year ago
      The conversation is about the potential risk of permanent hair loss from PRP (platelet rich plasma) treatments and whether PRF (platelet rich fibrin) carries the same risk. The user is seeking information on this topic.

      community Here is my hair regrowth plan

      in Treatment  3 upvotes 3 years ago
      The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 3 weeks ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  5 upvotes 7 months ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

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