TLDR Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.
Platelet-Rich Fibrin (PRF), a second-generation platelet concentrate, has shown potential in dermatology due to its high concentration of growth factors and cytokines. It has been used in the treatment of chronic wounds, androgenic alopecia (AGA), skin rejuvenation, autologous fat transplantation, and vitiligo treatment. PRF has shown to increase the speed of healing in chronic wounds, improve hair density in AGA treatment, and act as a natural filler in skin rejuvenation. In a clinical trial with 25 patients, PRF combined with fat was found to be more effective than fat and Platelet-Rich Plasma (PRP) in facial lipostructure surgery. However, the application of PRF in hair loss management is still in the early stages and requires further evaluation in high-quality randomized controlled trials. The document also highlights the need for a standardized protocol and large-scale studies for PRF treatment.
16 citations
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July 2018 in “Dermatologic Surgery” iL-PRF treatment improves hair growth for androgenetic alopecia.
54 citations
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May 2018 in “Journal of The European Academy of Dermatology and Venereology” Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
38 citations
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April 2018 in “Diseases” L-PRF treatment helped heal diabetic foot ulcers effectively.
214 citations
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September 2015 in “Stem Cells Translational Medicine” Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
20 citations
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October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
11 citations
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May 2021 in “Dermatologic clinics” PRP and cell therapies may help with hair loss, but more research is needed.
January 2023 in “Annali di stomatologia” PRP helps heal and repair tissues in medicine but needs more research for better use.
348 citations
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July 2017 in “Skin appendage disorders” Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.
4 citations
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September 2021 in “Biomolecules” Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
