Injectable Platelet-, Leukocyte-, and Fibrin-Rich Plasma in the Management of Androgenetic Alopecia

July 2018 in “ Dermatologic Surgery ”

Giovanni Schiavone, Andrea Paradisi, Francesco Ricci, Damiano Abeni

injectable platelet-rich plasma leukocyte-rich plasma fibrin-rich plasma iL-PRF androgenetic alopecia hair growth PRP AGA

Studysummary In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study investigated the effectiveness of injectable platelet-, leukocyte-, and fibrin-rich plasma (iL-PRF) in managing androgenetic alopecia (AGA). The results showed that iL-PRF treatment led to significant improvement in hair growth compared to the control group, regardless of the severity of the condition and sex. The study suggests that iL-PRF could be a promising treatment option for AGA.

View this study on journals.lww.com →

Discuss this study in the Community →

Research cited in this study

19 / 19 results

research Injections of Platelet-Rich Plasma for Androgenic Alopecia: A Systematic Review

25 citations , July 2017 in “Journal of Stomatology, Oral and Maxillofacial Surgery”

This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.

research Platelet-Rich Plasma for Androgenetic Alopecia: Does It Work? Evidence from Meta-Analysis

64 citations , March 2017 in “Journal of Cosmetic Dermatology”

This meta-analysis suggests that local injection of platelet-rich plasma for androgenic alopecia is associated with an increased number of hairs and some increase in hair thickness, though larger studies are needed for confirmation.

research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia

60 citations , September 2016 in “Dermatologic Surgery”

This article proposes a mechanistic model for how platelet-rich plasma therapy may stimulate hair growth in androgenetic alopecia by promoting vascularization and activating specific signaling pathways, but it reports no new experimental results.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

87 citations , September 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.

research Autologous Platelet-Rich Plasma for the Treatment of Pattern Hair Loss

42 citations , May 2016 in “American Journal of Clinical Dermatology”

This review discusses the use of platelet-rich plasma for pattern hair loss treatment and examines existing clinical studies without presenting new clinical results.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations , January 2015 in “International Journal of Trichology”

This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.

research Commentary on Platelet-Rich Plasma for Androgenetic Alopecia

6 citations , August 2014 in “Dermatologic Surgery”

PRP injections may improve hair loss condition, but more research needed.

research Platelet-Rich Plasma for Androgenetic Alopecia

107 citations , August 2014 in “Dermatologic Surgery”

This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.

research Platelet-Rich Fibrin Matrix for Androgenetic Alopecia

25 citations , May 2014 in “Facial Plastic Surgery”

In this study, intradermal injections of autologous platelet-rich fibrin matrix significantly increased hair density in patients with androgenetic alopecia at 2 and 3 months after initial treatment.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

115 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

In this study, PRP injections increased hair count and reduced hair loss in patients with androgenic alopecia not responding to minoxidil and finasteride, with high patient satisfaction reported.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

This study found that PRP injections may improve hair density and reduce hair loss in patients with androgenetic alopecia without significant side effects, but further research is needed to confirm efficacy.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations , December 2012 in “Journal of The European Academy of Dermatology and Venereology”

This study found that interfollicular injection of autologous CD34+ cell-containing PRP preparation improved hair count and thickness in patients with pattern hair loss, with better results than placental extract treatment.

research Role of Platelet-Rich Plasma in the Management of Androgenetic Alopecia

10 citations , January 2012 in “International Journal of Trichology”

PRP helps hair growth in common hair loss disorder.

research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

166 citations , August 2011 in “Dermatologic Surgery”

This study found that PRP combined with dalteparin and protamine microparticles may enhance hair growth by increasing hair thickness compared to PRP alone.

research Clinical Photography for Trichology Practice: Tips and Tricks

16 citations , January 2011 in “International Journal of Trichology”

This article discusses the principles and considerations of clinical photography for hair disorders in dermatology, reporting no new clinical findings.

research Automated Digital Image Analysis (TrichoScan) for Human Hair Growth Analysis: Ease Versus Errors

21 citations , January 2010 in “International Journal of Trichology”

This study concluded that TrichoScan is error-prone in its current form and overestimates certain hair growth parameters, with results not aligning with clinical severity of alopecia.

research Critical Study of Hair Growth Analysis with Computer-Assisted Methods

40 citations , April 2006 in “Journal of the European Academy of Dermatology and Venereology”

This study reported that Trichoscan, a computer-assisted hair measurement system, was not supported as accurate for clinical trials due to errors in signal detection, despite its analysis speed.

research Methods of Evaluating Hair Growth

63 citations , February 2003 in “Australasian Journal of Dermatology”

This review discusses various methods for measuring scalp hair growth in androgenetic alopecia and reports no new results; the authors suggest that computer-assisted technology has untapped potential.