Injections of Platelet-Rich Plasma for Androgenic Alopecia: A Systematic Review

July 2017 in “ Journal of Stomatology, Oral and Maxillofacial Surgery ”

Frederic Picard, Barbara Hersant, Jeremy Niddam, Jean-Paul Meningaud

platelet-rich plasma androgenic alopecia hair regrowth hair loss hair thickness hair density PRP

Studysummary This review suggests that PRP injections may be effective in promoting hair regrowth, reducing hair loss, and increasing hair thickness in patients with androgenic alopecia.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation

62 citations , October 2016 in “Dermatologic Therapy”

This study found that platelet-rich plasma was more effective for treating alopecia areata than topical 5% minoxidil, leading to earlier hair regrowth and reduction in hair abnormalities.

research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

87 citations , September 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.

research Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial

61 citations , September 2016 in “Journal of Cosmetic and Laser Therapy”

This study found that platelet-rich plasma was not effective in treating androgenetic alopecia in men with grade 4–6 hair loss.

research Meta-Analysis of Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia

57 citations , May 2016 in “Journal of Dermatological Treatment”

This analysis suggests that platelet-rich plasma therapy may be promising for treating androgenetic alopecia, but further controlled trials with standardized measures are needed to confirm its efficacy.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

research Management of Androgenetic Alopecia: A Comparative Clinical Study Between Plasma Rich in Growth Factors and Topical Minoxidil

8 citations , January 2016 in “European Journal of Plastic Surgery”

This study found that plasma rich in growth factors was a safe and more effective treatment for androgenetic alopecia than topical minoxidil, showing greater improvements in hair growth phases.

research The Success of Thread-Embedding Therapy in Generating Hair Regrowth in Mice Points to Its Possible Effect in Humans

20 citations , December 2015 in “Journal of Pharmacopuncture”

In this study, thread-embedding therapy enhanced hair regrowth in C57BL/6 mice by regulating growth factors associated with hair follicle anagen development and promoting cellular proliferation in hair follicles.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.

research Plasma Rich in Growth Factors for the Treatment of Androgenetic Alopecia

7 citations , June 2015 in “European Journal of Plastic Surgery”

This retrospective study found that treatment with autologous plasma rich in growth factors increased hair density and improved hair follicle health in patients with androgenetic alopecia, with no reported adverse effects.

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations , January 2015 in “International Journal of Trichology”

This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.

research Role of Platelet-Rich Plasma in Chronic Alopecia Areata: Our Centre Experience

61 citations , January 2015 in “Indian Journal of Plastic Surgery”

This study found that platelet-rich plasma may have a role in treating chronic alopecia areata, but more long-term follow-up studies are needed to confirm its effectiveness and success rate.

research Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia

74 citations , January 2015 in “Asian Journal of Transfusion Science”

This study found that platelet-rich plasma injections led to improvements in hair counts, thickness, and strength in patients with androgenic alopecia, showing promise as an effective treatment with no major adverse effects.

research Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss

54 citations , December 2014 in “Wound Repair and Regeneration”

This study observed that autologous PRP and PDRN injections improved hair thickness and density in women with pattern hair loss, with combined therapy showing greater improvement in thickness than PDRN alone.

research Platelet-Rich Plasma for Androgenetic Alopecia

107 citations , August 2014 in “Dermatologic Surgery”

This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.

research Platelet-Rich Fibrin Matrix for Androgenetic Alopecia

25 citations , May 2014 in “Facial Plastic Surgery”

In this study, intradermal injections of autologous platelet-rich fibrin matrix significantly increased hair density in patients with androgenetic alopecia at 2 and 3 months after initial treatment.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

115 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

In this study, PRP injections increased hair count and reduced hair loss in patients with androgenic alopecia not responding to minoxidil and finasteride, with high patient satisfaction reported.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

This study found that PRP injections may improve hair density and reduce hair loss in patients with androgenetic alopecia without significant side effects, but further research is needed to confirm efficacy.

research Promotional Effect of Platelet-Rich Plasma on Hair Follicle Reconstitution In Vivo

63 citations , October 2013 in “Dermatologic Surgery”

In this study using a mouse model, the researchers found that platelet-rich plasma significantly increased the number of newly formed hair follicles and decreased the time for hair formation compared to no treatment.

Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways

research Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways

39 citations , June 2013 in “Journal of Cosmetic Dermatology”

This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.

research Platelet-Rich Plasma Injection Is Effective and Safe for the Treatment of Alopecia

45 citations , March 2013 in “European Journal of Plastic Surgery”

In this retrospective study, PRP injections for alopecia were found to improve hair volume and quality, with high patient satisfaction, particularly in those with less than 2 years of hair loss.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations , December 2012 in “Journal of The European Academy of Dermatology and Venereology”

This study found that interfollicular injection of autologous CD34+ cell-containing PRP preparation improved hair count and thickness in patients with pattern hair loss, with better results than placental extract treatment.

research Letter: Platelet-Rich Plasma for Treating Male Pattern Baldness

36 citations , December 2012 in “Dermatologic Surgery”

Injecting platelet-rich plasma (PRP) can increase hair growth rate and density in male pattern baldness.

research Commentary on Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

13 citations , July 2012 in “Dermatologic Surgery”

Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.

research Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration

305 citations , June 2012 in “Nature”

This study reports that hair regeneration in live mice involves spatially regulated stem cell divisions and requires mesenchymal interactions, observed in real-time using a novel non-invasive imaging method.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , March 2012 in “Dermatologic Surgery”

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.

research Role of Platelet-Rich Plasma in the Management of Androgenetic Alopecia

10 citations , January 2012 in “International Journal of Trichology”

PRP helps hair growth in common hair loss disorder.

research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

166 citations , August 2011 in “Dermatologic Surgery”

This study found that PRP combined with dalteparin and protamine microparticles may enhance hair growth by increasing hair thickness compared to PRP alone.

research Epidermal Stem Cell Diversity and Quiescence

168 citations , August 2009 in “EMBO molecular medicine”

This review discusses epidermal stem cell diversity, revealing previously unrecognized differences in stem cell populations, but reports no new experimental results; it highlights the need for further exploration of stem cell interactions and quiescence.

research Hair Evaluation Methods: Merits and Demerits

91 citations , January 2009 in “International Journal of Trichology”

This review discusses the advantages and limitations of various hair loss evaluation methods but reports no new results; it emphasizes the importance of cautious interpretation for these diagnostic tools.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.

research Trichoscan: What Is New?

33 citations , January 2005 in “Dermatology”

This mini-review summarizes the Trichoscan as a sensitive tool for measuring hair growth parameters, demonstrating its effectiveness in detecting treatment response in androgenetic alopecia but noting some practical limitations.

research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations , January 2001 in “Cell”

This study demonstrated that multipotent stem cells in adult mice whisker follicles migrate to produce whisker growth, and that this process requires precise control of stem cell trafficking.

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

143 citations , October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.