Platelet-Rich Plasma: History of Platelet Concentrates and Current Applications in Medicine

    January 2023 in “ Annali di stomatologia ”
    M. Covelli
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    TLDR PRP helps heal and repair tissues in medicine but needs more research for better use.
    The document reviews the history and current applications of platelet-rich plasma (PRP) in medicine, emphasizing its regenerative potential in fields like surgery, dentistry, and orthopedics. PRP, rich in growth factors, enhances tissue healing and repair, with studies showing benefits in bone regeneration, muscle tissue repair, and treating androgenic alopecia. For example, in a study with 88 cases of mandibular reconstruction, PRP combined with bone grafts resulted in faster and better-quality bone regeneration. The paper also compares PRP with platelet-rich fibrin (PRF) and plasma rich in growth factors (PRGF), noting PRF's simpler preparation and higher growth factor content. Despite its benefits, PRP's use is limited by handling challenges, and further research is needed to optimize its application.
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