Platelet-Rich Plasma: History of Platelet Concentrates and Current Applications in Medicine
January 2023
in “
Annali di stomatologia
”
New to Platelet-Rich Plasma? There is a guide in the encyclopedia. Read the guide → 
Studysummary This review traces the development and application of Platelet-rich Plasma in regenerative medicine, emphasizing its role in tissue healing and bone regeneration, but reports no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.
The document reviews the history and current applications of platelet-rich plasma (PRP) in medicine, emphasizing its regenerative potential in fields like surgery, dentistry, and orthopedics. PRP, rich in growth factors, enhances tissue healing and repair, with studies showing benefits in bone regeneration, muscle tissue repair, and treating androgenic alopecia. For example, in a study with 88 cases of mandibular reconstruction, PRP combined with bone grafts resulted in faster and better-quality bone regeneration. The paper also compares PRP with platelet-rich fibrin (PRF) and plasma rich in growth factors (PRGF), noting PRF's simpler preparation and higher growth factor content. Despite its benefits, PRP's use is limited by handling challenges, and further research is needed to optimize its application.
