The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives

    September 2021 in “ Biomolecules ”
    Dimitris Tatsis, Varvara Vasalou, Efstathios Kotidis … Stamatios Angelopoulos
    Studysummary This review examines experimental studies on the synergistic use of platelet-rich plasma and adipose-derived mesenchymal stem cells for wound healing in animal models, without reporting new clinical outcomes.
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    Research cited in this study 7

    1. Adipose Mesenchymal Stem Cells Combined with Platelet-Rich Plasma Accelerate Diabetic Wound Healing by Modulating the Notch Pathway Stem Cell Research & Therapy · 2021
    2. Reporting in Clinical Studies on Platelet-Rich Plasma Therapy Among All Medical Specialties: A Systematic Review of Level I and II Studies PLOS ONE · 2021
    3. Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects International Journal of Molecular Sciences · 2021
    4. Regenerative Capacity of Adipose-Derived Stem Cells Compared with Mesenchymal Stem Cells International Journal of Molecular Sciences · 2019
    5. Effects of Storage Culture Media, Temperature, and Duration on Human Adipose-Derived Stem Cell Viability for Clinical Use Molecular Medicine Reports · 2019
    6. Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia Aesthetic Surgery Journal · 2018
    7. Fat, Stem Cells, and Platelet-Rich Plasma Clinics in Plastic Surgery · 2016