Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects

February 2021 in “ International Journal of Molecular Sciences ”

Pietro Gentile, Simone Garcovich

adipose-derived mesenchymal stem cells platelet-rich plasma biomaterials chronic skin wounds soft tissue defects diabetic foot ulcers vascular ulcers post-traumatic ulcers skin defects wound healing soft tissue volume improvement enzymatic digestion AD-MSCs PRP

Studysummary This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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research Systematic Review: Allogenic Use of Stromal Vascular Fraction and Decellularized Extracellular Matrices as Advanced Therapy Medicinal Products in Tissue Regeneration

113 citations , July 2020 in “International Journal of Molecular Sciences”

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research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy

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research Epithelial Differentiation of Human Adipose-Derived Stem Cells Undergoing Three-Dimensional Cultivation with Collagen Sponge Scaffold via an Indirect Co-Culture Strategy

48 citations , March 2020 in “Stem Cell Research & Therapy”

This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.

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research Impact of Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma and Activated Platelet-Rich Plasma in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation

58 citations , January 2020 in “International Journal of Molecular Sciences”

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research Impact of Different Preparation Methods to Obtain Human Adipose-Derived Stromal Vascular Fraction Cells and Human Adipose-Derived Mesenchymal Stem Cells: Enzymatic Digestion Versus Mechanical Centrifugation

124 citations , November 2019 in “International Journal of Molecular Sciences”

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Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

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