Human Hair Follicle-Derived Mesenchymal Stem Cells Promote Tendon Repair in a Rabbit Achilles Tendinopathy Model

April 2023 in “ Chinese Medical Journal ”

Yingyu Ma, Zhiwei Lin, Xiaoyi Chen, Xin Zhao, Yi Sun, Ji Wang, Xiaozhou Mou, Hai Zou, Jinyang Chen

human hair follicle-derived mesenchymal stem cells hHF-MSCs collagen fiber prokaryotic cell tendon repair Achilles tendinopathy regenerative treatment stem cells collagen

TLDR Human hair follicle stem cells help repair tendon injuries.

The study explored the effects of human hair follicle-derived mesenchymal stem cells (hHF-MSCs) on Achilles tendinopathy repair in rabbits. Results showed that hHF-MSCs significantly improved tendon repair, with better collagen fiber arrangement, increased prokaryotic cell numbers, and higher maximum tensile strength compared to untreated tendons. Molecular analyses revealed elevated expression of repair-related genes and proteins. These findings suggest that hHF-MSCs have potential as a regenerative treatment for tendon injuries.

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AIRMESS – Academy of International Regenerative Medicine & Surgery Societies: Recommendations in the Use of Platelet-Rich Plasma (PRP) and Autologous Stem Cell-Based Therapy (ASC-BT) in Androgenetic Alopecia and Wound Healing

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research Impact of Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma and Activated Platelet-Rich Plasma in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation

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Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.

Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development

136 citations, May 2019 in “Cells”

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research Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss

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research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine

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