Regenerative Capacity of Adipose-Derived Stem Cells Compared with Mesenchymal Stem Cells

The document reviewed the regenerative potential of adipose-derived stem cells (ADSCs) compared to mesenchymal stem cells (MSCs) from bone marrow and umbilical cord sources. ADSCs were noted for their accessibility, abundance, and ability to differentiate into various cell types, making them suitable for regenerative medicine. They showed promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, as well as in applications like wound healing and hair growth. ADSCs exhibited low immunogenicity, allowing for potential allogeneic transplantation without immunosuppression. Despite their advantages, challenges such as long-term culture effects and standardization for clinical use remained. Overall, ADSCs demonstrated significant regenerative capabilities, particularly through paracrine effects, across various medical applications.