September 2023 in “PubMed” In this study, researchers found that platelet-rich plasma therapy demonstrated significantly higher efficacy than topical minoxidil for treating androgenetic alopecia in a Pakistani population, with a 91.7% negative hair pull rate compared to 69.4% for minoxidil after 12 weeks.
June 2023 in “Skin Research and Technology” This study concluded that, in male patients with mild-to-moderate androgenetic alopecia, injections of PRP prepared by an automated method combined with topical 5% minoxidil were effective and safe, showing superior clinical efficacy and patient satisfaction compared to PRP alone.
This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.
February 2023 in “Journal of Dermatological Treatment” In this study, both platelet-rich plasma and minoxidil increased hair counts and density in moderate androgenetic alopecia in men, but patient satisfaction was higher with minoxidil, which also had fewer side effects.
1 citations
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January 2023 in “PubMed” This systematic review and meta-analysis found limited, low-quality evidence suggesting that platelet-rich plasma injections may increase hair density in patients with androgenetic alopecia compared to saline, but results were inconclusive for alopecia areata.
1 citations
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December 2022 in “Archives of Dermatological Research” This study compared fluid PRF and PRP for treating atrophic acne scars and found PRF to be more effective, particularly when combined with needling. Both treatments improved scars, but PRF showed higher therapeutic response, suggesting it as a superior alternative for acne scar treatment.
1 citations
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November 2022 in “Journal of Dermatological Treatment” This review discusses the use of platelet-rich plasma for various dermatologic conditions but reports inconsistent evidence and a lack of standardized protocols; patients often report high satisfaction despite mixed clinical outcomes.
June 2022 in “International Journal of Research in Dermatology” This study found that injectable platelet-rich fibrin significantly improved hair growth and patient satisfaction as a cost-effective adjuvant treatment for androgenetic alopecia.
1 citations
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April 2022 in “Journal of Cosmetic Dermatology” This review highlights that androgenetic alopecia significantly impacts psychological well-being and quality of life, emphasizing the need for integrated psychological support alongside dermatological treatment.
1 citations
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January 2022 in “Journal of Cutaneous and Aesthetic Surgery” This study found that adding platelet-rich plasma to 5% minoxidil treatment improved hair growth outcomes in patients with androgenetic alopecia compared to minoxidil alone.
5 citations
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November 2021 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This study found that platelet-rich plasma was safe and effective for treating female androgenetic alopecia, presenting a promising alternative to traditional medications like Minoxidil® and Finasteride®.
3 citations
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October 2021 in “Dermatologic Therapy” This study demonstrated that PRP treatment improved hair metrics in androgenetic alopecia, with the dermapen method proving more effective than the point-by-point technique for specific hair growth indicators.
2 citations
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October 2021 in “Experimental Cell Research” This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.
6 citations
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May 2021 in “Aesthetic Surgery Journal” This study found that intradermal injections of platelet-rich plasma were equally safe and effective for treating androgenetic alopecia, with higher platelet numbers possibly enhancing hair density and follicle diameter.
70 citations
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February 2021 in “International Journal of Molecular Sciences” This review provides an overview of current research on AD-MSCs, PRP, and biomaterials, highlighting their safety and efficacy in treating soft tissue defects and chronic wounds without major side effects.
1 citations
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January 2021 in “Indian Dermatology Online Journal” This expert group provided recommendations for preparing and using platelet-rich plasma in treating androgenetic alopecia, suggesting a manual double-spin method and specific dosing, although further studies on injectable platelet-rich fibrin are needed.
23 citations
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September 2020 in “Journal of Cosmetic Dermatology” This review discusses the potential applications of injectable platelet‐rich fibrin in various conditions and reports no new clinical results; the authors highlight its favorable use in comparison to existing treatments.
13 citations
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September 2020 in “International Journal of Molecular Sciences” This study found that combining platelet-rich plasma therapy with minoxidil was more effective in treating androgenetic alopecia in men than either treatment alone.
115 citations
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August 2020 in “International Journal of Molecular Sciences” This systematic review indicates that a platelet-rich plasma concentration of 1.0 × 10^6 plt/μL may be optimal for tissue regeneration due to sufficient nutrition supply and effective growth factor diffusion in vivo.
33 citations
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July 2020 in “Journal of The American Academy of Dermatology” In this study, PRP increased hair density in areas treated for androgenetic alopecia, but there was no significant difference when compared to placebo-treated areas.
65 citations
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April 2020 in “International Journal of Molecular Sciences” This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.
15 citations
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March 2020 in “Journal of cosmetic dermatology” This review examines non-surgical methods for rejuvenating the periorbital area and highlights the growing role of platelet-rich plasma, but it reports no new clinical findings.
40 citations
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February 2020 in “Experimental and Therapeutic Medicine” This study found that autologous serum platelet-rich plasma improved skin quality and reduced wrinkles, texture, and pores in healthy females, partly by regulating the expression of MMP-1, tyrosinase, fibrillin, and tropoelastin.
44 citations
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February 2020 in “Expert Opinion on Biological Therapy” In this study, autologous non-activated platelet-rich plasma was associated with greater hair re-growth than autologous activated platelet-rich plasma over long-term follow-up.
26 citations
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December 2019 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that platelet-rich plasma combined with topical minoxidil was more effective in increasing hair density for male-type baldness than either treatment alone.
1 citations
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September 2019 This review discusses platelet-rich plasma and microneedling as potential regenerative therapies for hair loss disorders but reports no new clinical results; the authors suggest using these approaches alongside existing treatments.
25 citations
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September 2019 in “PubMed” This review discusses the therapeutic potential of platelet-rich plasma in dermatology and highlights the need for standardized treatment protocols, but reports no new clinical results.
6 citations
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September 2019 in “Indian Journal of Dermatology” 
69 citations
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April 2019 in “Biomedicines” This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.
18 citations
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January 2019 in “International journal of trichology” This study found that injectable platelet-rich fibrin (i-PRF) showed improved hair growth in males with Type VI and Type VII alopecia, which are typically difficult to treat.
1 citations
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January 2019 in “Journal of Biomedical Science and Engineering” This study reports that monthly subcutaneous injections of concentrated growth factors improved hair appearance and density in patients with androgenetic alopecia, with no side effects observed in the follow-up period.
18 citations
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January 2019 in “International Journal of Trichology” This study found that PRP therapy resulted in better hair growth and patient satisfaction than minoxidil therapy in men with androgenetic alopecia over six months, and patients with higher platelet counts in PRP experienced greater improvement.
51 citations
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November 2018 in “JAMA Dermatology” This study found that participant self-assessments suggested greater improvement in the texture and wrinkles of facial skin treated with PRP compared to normal saline, though dermatologist ratings showed no significant difference.
57 citations
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October 2018 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma significantly increased hair count, density, and the percentage of anagen hairs in patients with androgenetic alopecia, but these improvements did not correlate with platelet or growth factor levels.
18 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.
16 citations
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July 2018 in “Dermatologic Surgery” In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.
58 citations
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February 2018 in “Journal of cosmetic dermatology” This review explores how estrogens influence skin health and attractiveness in women, particularly with aging, but it reports no new clinical findings.
January 2018 in “Journal of Visualized Experiments” This study found that injections of autologous platelet-rich plasma in patients with pattern hair loss were compared to placebo, but the abstract does not report specific clinical results.
52 citations
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May 2017 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly improved hair density, thickness, and patient satisfaction in women with female pattern hair loss compared to a placebo.
70 citations
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February 2017 in “Dermatologic Surgery” This study reports that plasma rich in growth factors appeared to improve hair follicle regeneration and patient satisfaction in individuals with androgenetic alopecia, though further trials are needed.
136 citations
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February 2017 in “International Journal of Molecular Sciences” This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.
87 citations
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September 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.
61 citations
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September 2016 in “Journal of Cosmetic and Laser Therapy” This study found that platelet-rich plasma was not effective in treating androgenetic alopecia in men with grade 4–6 hair loss.
4 citations
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September 2016 in “PubMed” In this study, platelet-rich fibrin matrix combined with follicular unit transplantation increased hair follicle numbers in men with androgenetic alopecia on the treated side of the scalp after six months.
136 citations
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April 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
106 citations
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January 2016 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.
101 citations
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January 2016 in “Journal of Cutaneous and Aesthetic Surgery” This review discusses various classification systems for patterned hair loss in both sexes and reports no new clinical findings, highlighting the Hamilton-Norwood and Ludwig systems as the most commonly used.
214 citations
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September 2015 in “Stem Cells Translational Medicine” This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.
25 citations
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June 2015 in “Seminars in Cutaneous Medicine and Surgery” This article discusses methods to distinguish and manage female pattern alopecia and telogen effluvium in women with diffuse hair loss but reports no new clinical results.
54 citations
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December 2014 in “Wound Repair and Regeneration” This study observed that autologous PRP and PDRN injections improved hair thickness and density in women with pattern hair loss, with combined therapy showing greater improvement in thickness than PDRN alone.
25 citations
,
May 2014 in “Facial Plastic Surgery” In this study, intradermal injections of autologous platelet-rich fibrin matrix significantly increased hair density in patients with androgenetic alopecia at 2 and 3 months after initial treatment.
183 citations
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January 2014 in “BioMed Research International” This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.
91 citations
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January 2009 in “International Journal of Trichology” This review discusses the advantages and limitations of various hair loss evaluation methods but reports no new results; it emphasizes the importance of cautious interpretation for these diagnostic tools.
41 citations
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January 2009 in “International Journal of Trichology” This study found that 58% of men aged 30-50 had androgenic alopecia, with disease severity increasing with age and many being candidates for medical treatment or hair transplantation.
