Platelet-Rich Fibrin: A Second-Generation Autologous Platelet Concentrate

    May 2022 in “ Advances in Cosmetic Surgery ”
    Taryn Murray, Shilpi Khetarpal
    Image of study
    TLDR Platelet-rich fibrin helps in healing and rejuvenation but results vary and can take time.
    Platelet-rich fibrin (PRF) is a second-generation autologous platelet concentrate that naturally contains a fibrin clot and does not require an anticoagulant. It contains more concentrated platelets and growth factors than platelet-rich plasma (PRP), and its fibrin clot results in a slow and sustained release of growth factors. PRF has been successful in postprocedural wound healing, hair restoration, skin rejuvenation, and dermal augmentation. However, results from PRF are highly variable and may take several months to become noticeable. Not all patients respond to treatment. Treatments with autologous platelet concentrates are generally safe, with risks including infection, pain, and bleeding. Despite its benefits, the results of PRF can be unpredictable due to various factors.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 93 results

      community Hairloss after doing PRF treatment

      in Treatment  2 upvotes 1 year ago
      The conversation is about the potential risk of permanent hair loss from PRP (platelet rich plasma) treatments and whether PRF (platelet rich fibrin) carries the same risk. The user is seeking information on this topic.

      community Here is my hair regrowth plan

      in Treatment  4 upvotes 4 years ago
      The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

      community I have been on finasteride for 9 months. (6 months on 0.25 mg, 3 months into 0.5 mg daily) here are the progress pictures.

      in Progress Pictures  273 upvotes 1 week ago
      A user shared progress pictures after 9 months on finasteride, starting with 0.25 mg and increasing to 0.5 mg daily, noting improved hair density, especially at the crown, with initial side effects that resolved after the first month. The discussion includes user experiences with finasteride, concerns about side effects, and alternative treatments like rosemary oil and platelet-rich plasma therapy.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 7 months ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

    Similar Research

    6 / 1000+ results