Platelet Preparations for Use in Facial Rejuvenation and Wound Healing: A Critical Review of Current Literature

    June 2015 in “ Aesthetic Plastic Surgery ”
    Anthony P. Sclafani, James Azzi
    Image of study
    TLDR Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
    The document critically reviews the use of platelet preparations, including platelet-rich plasma (PRP) and platelet-rich fibrin matrix (PRFM), in facial rejuvenation and wound healing. It compiles findings from 61 reports, including in vitro studies, animal studies, and case series/clinical trials. The majority of these studies show positive effects of platelet preparations on cellular activity, wound healing, and aesthetic outcomes, such as enhanced fat graft survival, increased hair follicle formation, and improved skin conditions post-laser resurfacing. Some studies specifically highlight the potential of PRP in treating androgenetic alopecia by increasing hair density and count. Despite the favorable outcomes, the review points out the possibility of publication bias and the need for more robust randomized controlled trials with objective measures to fully ascertain the efficacy of platelet preparations in medical applications, including their role in hair loss treatment.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 79 results

      community Hairloss after doing PRF treatment

      in Treatment  2 upvotes 1 year ago
      The conversation is about the potential risk of permanent hair loss from PRP (platelet rich plasma) treatments and whether PRF (platelet rich fibrin) carries the same risk. The user is seeking information on this topic.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 1 year ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 month ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community PRP + GFC for hair regrowth?..

      in Treatment  2 upvotes 9 months ago
      A dermatologist recommended PRP (Platelet Rich Plasma) and GFC (Growth Factor Concentrate) for pattern baldness, but online sources suggest they may not be effective. The user is seeking opinions on these treatments.

    Related Research

    2 / 2 results