Regenerative Treatments: Microneedling and PRP

September 2019

Colombina Vincenzi, Benedetta Marisaldi, Antonellá Tosti

platelet-rich plasma microneedling follicular regeneration hair loss disorders dermatology PRP

TLDR PRP and microneedling may help with hair loss, but more research is needed.

The document discussed the use of platelet-rich plasma (PRP) and microneedling as emerging regenerative therapies for hair loss disorders. These treatments, initially used in other medical fields, gained popularity in dermatology for their potential to stimulate follicular regeneration. Although several studies and case reports indicated their therapeutic effectiveness, the document emphasized the need for more evidence-based studies to confirm their benefits. The authors suggested using PRP and microneedling in conjunction with existing hair growth-promoting therapies or as standalone treatments when medical treatments are contraindicated.

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Research cited in this study

16 / 16 results

research Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia Along with Dermoscopic Pre- and Post-Treatment Evaluation

36 citations , August 2017 in “Journal of Cosmetic Dermatology”

PRP with microneedling effectively treats hair loss, and dermoscopy helps evaluate results.

research Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

53 citations , June 2017 in “Skin appendage disorders”

PRP treatment helps hair growth in most cases, but more research needed.

research Microneedling: Current Status and Systematic Literature Review

92 citations , June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery”

Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.

A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

research A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia

48 citations , January 2017 in “International Journal of Trichology”

Microneedling with platelet-rich plasma and minoxidil improves hair growth more than just minoxidil in men with hair loss.

research Platelet-Rich Plasma Versus Minoxidil 5% in Treatment of Alopecia Areata: A Trichoscopic Evaluation

62 citations , October 2016 in “Dermatologic Therapy”

PRP more effective than minoxidil 5% for treating alopecia areata.

research A Mechanistic Model of Platelet-Rich Plasma Treatment for Androgenetic Alopecia

60 citations , September 2016 in “Dermatologic Surgery”

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns

research Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns

49 citations , August 2016 in “Aesthetic Surgery Journal”

Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.

research Platelet-Rich Plasma as a Novel Treatment for Lichen Planopillaris

29 citations , March 2016 in “Dermatologic therapy”

Platelet-rich plasma may successfully treat lichen planopillaris, as shown by one patient's symptom regression.

research Platelet-Rich Plasma Microneedling Versus 5% Topical Minoxidil in the Treatment of Patterned Hair Loss

13 citations , January 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Minoxidil works faster and is more cost-effective for treating hair loss, but platelet-rich plasma microneedling can be an alternative for those who can't use minoxidil.

research Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy

68 citations , May 2015 in “Indian Journal of Dermatology”

Microneedling can effectively promote new hair growth in men with hair loss who didn't improve with traditional treatments.

research Alopecia Areata: Successful Outcome with Microneedling and Triamcinolone Acetonide

53 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Microneedling combined with triamcinolone can safely stimulate faster hair regrowth in people with Alopecia Areata.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations , January 2013 in “International Journal of Trichology”

Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study

research Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study

34 citations , October 2012 in “Journal of Dermatology”

Growth factors and microneedle therapy increase hair density in women with hair loss.

research Management of Primary Cicatricial Alopecias: Options for Treatment

98 citations , May 2008 in “British Journal of Dermatology”

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

Related Research

6 / 6 results

research Hair Loss

August 2021 in “Pharmacy Today”

The document's conclusion about hair loss cannot be determined.

research Hair Loss: Causes and Pathology

June 2021 in “International Journal of Research in Medical Sciences & Technology”

Hair loss has many causes and needs specific treatments.

research Diffuse Hair Loss

June 2021 in “Elsevier eBooks”

The document's conclusion cannot be summarized because it is not readable or understandable.

research Platelet-Rich Plasma Effect on Androgenetic Alopecia and Female Pattern Hair Loss

1 citations , December 2019 in “Journal of skin and stem cell”

PRP shows promise for short-term hair growth, especially in young men.

research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations , November 2017 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.

research A Review on Hair Loss and Damage

January 2016

The article concludes that understanding the causes of hair loss and using continuous treatments like minoxidil and finasteride can help manage it, despite potential side effects.