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    GlossaryAlopecia (Hair Loss Disorders)

    refers to hair loss from areas where hair normally grows

    Alopecia refers to the partial or complete loss of hair from areas of the body where it typically grows, most commonly the scalp. It can be caused by a variety of factors including genetics, autoimmune disorders, hormonal changes, and environmental influences. There are different types of alopecia, such as alopecia areata, which is an autoimmune condition where the immune system attacks hair follicles, leading to patchy hair loss.

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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Castor oil

      a traditional, natural remedy touted for promoting scalp health and hair growth

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 2 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How uninformed the general public is about hair loss

      in Chat  315 upvotes 9 months ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

      community I tried salt water to stop the DHT itch

      in Treatment  60 upvotes 1 year ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

      community CRISPR treatment for AGA on the horizon after approval for blood disorders

      in Treatment  11 upvotes 8 months ago
      CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.