Injectable Platelet Rich Fibrin Facilitates Hair Follicle Regeneration by Promoting Human Dermal Papilla Cell Proliferation, Migration, and Trichogenic Inductivity

    October 2021 in “ Experimental Cell Research ”
    Kongye Lu, Qi-Wen Han, Zekun Ma … Tuanjie Hou
    Studysummary This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Detecting the Mechanism Behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus Nippon) Dermal Papilla Cells to Three-Dimensional Pattern International Journal of Molecular Sciences · 2021
    2. Maintaining Inducibility of Dermal Follicle Cells on Silk Fibroin/Sodium Alginate Scaffold for Enhanced Hair Follicle Regeneration Biology · 2021
    3. Platelet-Rich Plasma: Evolving Role in Plastic Surgery Plastic and Reconstructive Surgery · 2020
    4. Isolating Dermal Papilla Cells from Human Hair Follicles Using Microdissection and Enzyme Digestion Methods in molecular biology · 2020
    5. Tissue Engineering Strategies for Human Hair Follicle Regeneration: How Far From a Hairy Goal? Stem Cells Translational Medicine · 2019
    6. Keratinocytes Maintain Compartmentalization Between Dermal Papilla and Fibroblasts in 3D Heterotypic Tri-Cultures Cell Proliferation · 2019
    7. Use of Extracellular Matrix Hydrogel from Human Placenta to Restore Hair-Inductive Potential of Dermal Papilla Cells Regenerative Medicine · 2019
    8. Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation Biomedicines · 2019
    9. The Mechanism of Activated Platelet-Rich Plasma Supernatant Promotion of Hair Growth by Cultured Dermal Papilla Cells Journal of Cosmetic Dermatology · 2019
    10. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth International Journal of Cosmetic Science · 2018
    11. A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification Skin appendage disorders · 2017
    12. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    13. Hair Follicle: A Novel Source of Multipotent Stem Cells for Tissue Engineering and Regenerative Medicine Tissue Engineering Part B-reviews · 2012
    14. The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization Experimental Dermatology · 2009

    Related research 1

    1. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010