Tissue Engineering Strategies for Human Hair Follicle Regeneration: How Far From a Hairy Goal?

    December 2019 in “ Stem Cells Translational Medicine
    Ana María Porto Castro, Elsa Logarinho
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    TLDR Fully regenerating human hair follicles not yet achieved.
    This document is a compilation of various articles discussing tissue engineering strategies for human hair follicle regeneration. While progress has been made, the goal of fully regenerating human hair follicles is still far from being achieved. The articles explore different approaches and challenges, including the need for further research, the importance of stem cells and dermal papilla cells, and the role of receptive epithelial cells and signaling modulation. Some studies have shown success in growing mouse hair in vivo after transplantation of in vitro formed structures, but achieving fully functional hair follicle regeneration in humans remains a distant goal.
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