TSA Restores Hair Follicle-Inductive Capacity of Skin-Derived Precursors

    February 2019 in “ Scientific Reports ”
    Ling Guo, Xiaoxiao Wang, Jifan Yuan … Yaojiong Wu
    Studysummary This study found that TSA restored the hair-inductive capacity of skin-derived precursors in mice by enhancing BMP gene expression and signaling through histone acetylation.
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    Research cited in this study 8

    1. Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors Stem cells translational medicine · 2016
    2. Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors Stem Cells Translational Medicine · 2016
    3. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    4. Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach Journal of Investigative Dermatology · 2013
    5. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011
    6. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009
    7. Hair Follicle Neogenesis Induced by Cultured Human Scalp Dermal Papilla Cells Regenerative Medicine · 2009
    8. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003