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Did you mean Histone Deacetylases?

GlossaryHistone Deacetylases

enzymes that remove acetyl groups from histone proteins

Histone Deacetylases (HDACs) are enzymes that remove acetyl groups from histone proteins, leading to a more compact and less accessible form of DNA. This process can suppress gene expression by making it harder for transcription factors to access the DNA. HDACs play a crucial role in regulating gene activity and are involved in various biological processes, including cell cycle progression and differentiation.

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learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

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research Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System

8 citations, October 2019 in “The Journal of surgical research/Journal of surgical research”

Sodium valproate helps skin healing by affecting GABA and histone deacetylase.

research TSA Restores Hair Follicle-Inductive Capacity of Skin-Derived Precursors

18 citations, February 2019 in “Scientific Reports”

Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.

Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

research Short-Chain Fatty Acids from Cutibacterium Acnes Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes

70 citations, February 2019 in “The journal of immunology/The Journal of immunology”

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

research Small RNAs Loom Large During Reprogramming

18 citations, June 2011 in “Cell stem cell”

MicroRNAs can reprogram cells into stem cells faster and more efficiently than traditional methods.

research Glucose Metabolism Regulates Expression of Hair-Inductive Genes of Dermal Papilla Spheres via Histone Acetylation

6 citations, March 2020 in “Scientific reports”

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

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community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?

in Research/Science 3 upvotes 1 year ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.