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    Glossary Enhancer of Zeste Homolog 2

    gene encoding an enzyme that represses gene expression via methylation

    Enhancer of Zeste Homolog 2 (EZH2) is a gene that encodes an enzyme involved in modifying chromatin, which is the complex of DNA and proteins in the cell nucleus. This enzyme adds methyl groups to histone proteins, leading to the repression of gene expression. EZH2 is important in regulating cell division and differentiation, and its dysregulation is often associated with various cancers.

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    1. 102 EZH2 is required for human hair follicle growth and epidermal differentiation Journal of Investigative Dermatology · 2016
    2. EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression Aging · 2020 · 12 citations
    3. Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma 2023
    4. Botulinum Neurotoxin Type A Combined with Platelet-Rich Plasma Promotes Hair Follicle Growth and Regeneration via STMN1 Modulation and Wnt/β-Catenin Pathway Activation Journal of Microbiology and Biotechnology · 2025
    5. Stem Cells on Alert: Priming Quiescent Stem Cells after Remote Injury Cell stem cell · 2014 · 13 citations
    6. Tumor Angiogenesis and Anti-angiogenic Therapy The Keio Journal of Medicine · 2012 · 123 citations
    7. Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation Cells · 2025 · 5 citations
    8. Wnt signaling: the good and the bad Acta Biochimica et Biophysica Sinica · 2008 · 48 citations
    9. Small molecules and small molecule drugs in regenerative medicine Drug Discovery Today · 2013 · 51 citations
    10. Oncogenic senescence: a multi-functional perspective Oncotarget · 2017 · 32 citations
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